Synonym: N-(3α,7β-Dihydroxy-5β-cholan-24-oyl)glycine; N-[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine; GUDCA; Glycylursodeoxycholic acid; Ursodeoxycholylglycine
CAS Number: 64480-66-6
Empirical Formula (Hill Notation): C26H43NO5
Molecular Weight: 449.62
MDL Number: MFCD00137427
Linear Formula: C26H43NO5
Product Type: Chemical
| assay |
≥96.0% (TLC) |
| biological source |
synthetic |
| form |
powder |
| functional group |
carboxylic acid |
| InChI |
1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21+,24+,25+,26-/m1/s1 |
| InChI key |
GHCZAUBVMUEKKP-XROMFQGDSA-N |
| Quality Level |
100  |
| SMILES string |
[H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(NCC(O)=O)=O |
| Application: |
- Glycoursodeoxycholic Acid Alleviates Arterial Thrombosis via Suppressing Diacylglycerol Kinases Activity in Platelet.: Highlights the therapeutic potential of Glycoursodeoxycholic acid in alleviating arterial thrombosis by inhibiting diacylglycerol kinase activity in platelets (Yang et al., 2024
 ).
|
| Biochem/physiol Actions: |
Secondary bile acid derived from acyl glycine. Glycoursodeoxycholic Acid (GUDCA) is reported to have cytoprotective and anti-inflammatory effects. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥96.0% (TLC) |
| UNSPSC |
12161900 |
