(R)-(+)-α-Lipoic acid
SIGMA/07039 - ≥98.0% (HPLC)
Synonym: (R)
CAS Number: 1200-22-2
Empirical Formula (Hill Notation): C8H14O2S2
Molecular Weight: 206.33
MDL Number: MFCD01631142
Linear Formula: C8H14O2S2
Product Type: Chemical
| assay | ≥98.0% (HPLC) |
| InChI | 1S/C8H14O2S2/c9-8(10)4-2- |
| InChI key | AGBQKNBQESQNJD-SSDOTTSWSA |
| mp | 48-52 °C (lit.) |
| optical purity | enantiomeric excess: ≥98.0% (HPLC) |
| Quality Level | 100  |
| 200 |
|
| SMILES string | OC(=O)CCCC[C@@H]1CCSS1 |
| storage temp. | −20°C |
| Analysis Note: | identity confirmed by LC-MS |
| Biochem/physiol Actions: | (R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease. |
| Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.0% (HPLC) |
| mp | 48-52 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |