(R)-(+)-α-Lipoic acid

SIGMA/07039 - ≥98.0% (HPLC)

Synonym: (R)-(+)-1,2-Dithiolane-3-pentanoic acid; (R)-6,8-Dithiooctanoic acid; (R)-6,8-Thioctic acid

CAS Number: 1200-22-2
Empirical Formula (Hill Notation): C₈H₁₄O₂S₂
Molecular Weight: 206.33
MDL Number: MFCD01631142
Linear Formula: C₈H₁₄O₂S₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-07039-10MG	10 mg	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-07039-50MG	50 mg	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-07039-500MG	500 mg	$1070.00 1/EAAdd To Favorites	Add To Favorites

assay	≥98.0% (HPLC)
InChI	1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
InChI key	AGBQKNBQESQNJD-SSDOTTSWSA-N
mp	48-52 °C (lit.)
optical purity	enantiomeric excess: ≥98.0% (HPLC)
Quality Level	100
	200
SMILES string	OC(=O)CCCC[C@@H]1CCSS1
storage temp.	−20°C

Analysis Note:	identity confirmed by LC-MS
Biochem/physiol Actions:	(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease.
Packaging:	Bottomless glass bottle. Contents are inside inserted fused cone.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98.0% (HPLC)
mp	48-52 °C (lit.)
Storage Temp.	−20°C
UNSPSC	12352202