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(R)-Mevalonic acid 5-phosphate lithium salt

SIGMA/07841 - 95% (TLC)

Synonym: (R)-3-Hydroxy-3-methyl-5-phosphonooxy-pentanoic acid lithium salt; (R)-5-Phosphomevalonate lithium salt; R-MVAP-Li

CAS Number: 73566-35-5 (free acid)
Empirical Formula (Hill Notation): C6H13O7P · xLi+
Molecular Weight: 228.14 (free acid basis)
Linear Formula: C6H13O7P · xLi+
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-07841-10MG 10 mg
 $646.00
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assay 95% (TLC)
InChI 1S/C6H13O7P/c1-6(9,4-5(7)8)2-3-13-14(10,11)12/h9H,2-4H2,1H3,(H,7,8)(H2,10,11,12)/p-3/t6-/m1/s1
InChI key OKZYCXHTTZZYSK-ZCFIWIBFSA-K
optical activity [α]/D -3.2±0.5°, c = 0.1 in 0.2 M HCl
Quality Level 100 
storage temp. −20°C
Application: Mevalonic acid 5-phosphate (M5P) may be used as a reference material in assays for the separation or detection of mevalonic acid 5-phosphate. Mevalonic acid 5-phosphate is the immediate precursor of isopentenyl pyrophosphate (IPP) and the mevalonate pathway which leads to isoprenoid biosynthesis. Mevalonic acid 5-phosphate may be used as a substrate to identify and characterize phosphomevalonate kinase(s).
Biochem/physiol Actions: Metabolite of the mevalonate pathway, which plays a key role in the biosynthesis of sterols, dolichol, heme and ubiquinone. Of interest for research in the disease areas oncology, autoimmune diseases, artherosclerosis and Alzheimer disease, as well as for inherited deficiencies of mevalonate kinase.
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity 95% (TLC)
Storage Temp. −20°C
UNSPSC 12352106

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