(R)-Mevalonic acid 5-phosphate lithium salt

SIGMA/07841 - 95% (TLC)

Synonym: (R)-3-Hydroxy-3-methyl-5-phosphonooxy-pentanoic acid lithium salt; (R)-5-Phosphomevalonate lithium salt; R-MVAP-Li

CAS Number: 73566-35-5 (free acid)
Empirical Formula (Hill Notation): C₆H₁₃O₇P · xLi⁺
Molecular Weight: 228.14 (free acid basis)
Linear Formula: C₆H₁₃O₇P · xLi⁺
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-07841-10MG	10 mg	$664.00 1/EAAdd To Favorites	Add To Favorites

assay	95% (TLC)
InChI	1S/C6H13O7P/c1-6(9,4-5(7)8)2-3-13-14(10,11)12/h9H,2-4H2,1H3,(H,7,8)(H2,10,11,12)/p-3/t6-/m1/s1
InChI key	OKZYCXHTTZZYSK-ZCFIWIBFSA-K
optical activity	[α]/D -3.2±0.5°, c = 0.1 in 0.2 M HCl
Quality Level	100
storage temp.	−20°C

Application:	Mevalonic acid 5-phosphate (M5P) may be used as a reference material in assays for the separation or detection of mevalonic acid 5-phosphate. Mevalonic acid 5-phosphate is the immediate precursor of isopentenyl pyrophosphate (IPP) and the mevalonate pathway which leads to isoprenoid biosynthesis. Mevalonic acid 5-phosphate may be used as a substrate to identify and characterize phosphomevalonate kinase(s).
Biochem/physiol Actions:	Metabolite of the mevalonate pathway, which plays a key role in the biosynthesis of sterols, dolichol, heme and ubiquinone. Of interest for research in the disease areas oncology, autoimmune diseases, artherosclerosis and Alzheimer disease, as well as for inherited deficiencies of mevalonate kinase.
Packaging:	Bottomless glass bottle. Contents are inside inserted fused cone.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	95% (TLC)
Storage Temp.	−20°C
UNSPSC	12352106