MS-1 cell line

SIGMA/09111802

Synonym: MS1 Cells

Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-09111802-1VL	1 vial	$0.00 1/EA CALL FOR PRICEAdd To Favorites		Add To Favorites

biological source	human skin
form	liquid
growth mode	Suspension
karyotype	Not determined
morphology	Loosely packed floating aggregates with irregular outline and no central necrosis
products	Cell line is CM2B4/MCV T, AE1/AE2, CK20, EMA, CAM5.2, chromogranin & NSE. Cell line is negative for for CK7, synaptophysin, LCA TTF-1, vimentin and CD99,
Quality Level	100
receptors	Not specified
relevant disease(s)	cancer
shipped in	dry ice
storage temp.	−196°C
technique(s)	cell culture \| mammalian: suitable

Application:	Pathobiology of neuroendocrine skin carcinomas (NSCs) and function of cutaneous Merkel cells. The role of polyomavirus in the development of Merkel cell carcinomas (submitted for publication)
Cell Line Description:	MS-1 cells contain a Merkel cell polyomavirus integrated into the genome. See also MKL-1 (Sigma Catalogue number 09111801).
Cell Line Origin:	Human neuroendocrine skin carcinoma
Culture Medium:	RPMI 1640 + 2mM Glutamine + 20% Foetal Bovine Serum (FBS).
Disclaimer:	RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
DNA Profile:	STR-PCR Data: Amelogenin: X CSF1PO: 10 D13S317: 11,14 D16S539: 9 D5S818: 11 D7S820: 8,9 THO1: 7,9.3 TPOX: 8 vWA: 17
Other Notes:	Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.
Other Notes:	Cultures from HPA Culture Collections and supplied by Sigma are for research purposes only. Enquiries regarding the commercial use of a cell line are referred to the depositor of the cell line. Some cell lines have additional special release conditions such as the requirement for a material transfer agreement to be completed by the potential recipient prior to the supply of the cell line. Please view the Terms & Conditions of Supply for more information.
Other Notes:	Depositor and originator: Dr Patrick Moore, University of Pittsburgh Cancer Institute, 5117 Centre Avenue Suite 1.8 Pittsburgh PA 15213
Subculture Routine:	Seed at 3 x 10⁵ cells/ml in 5% CO₂; 37°C Saturation density is approximately 10⁶ cells/ml.