4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester

SIGMA/09278 - ≥98.0% (HPLC)

Synonym: 4-(Dimethylamino)azobenzene-4′-carboxylic acid N-succinimidyl ester; DABCYL-N-succinimidyl ester

CAS Number: 146998-31-4
Empirical Formula (Hill Notation): C₁₉H₁₈N₄O₄
Molecular Weight: 366.37
MDL Number: MFCD00467415
Linear Formula: C₁₉H₁₈N₄O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-09278-25MG-F	25 mg	$112.00 1/EAAdd To Favorites	Add To Favorites
45-09278-100MG-F	100 mg	$332.00 1/EAAdd To Favorites	Add To Favorites

assay	≥98.0% (HPLC)
fluorescence	λ_ex 428 nm; λ_em 453 nm
form	powder
InChI	1S/C19H18N4O4/c1-22(2)16-9-7-15(8-10-16)21-20-14-5-3-13(4-6-14)19(26)27-23-17(24)11-12-18(23)25/h3-10H,11-12H2,1-2H3/b21-20+
InChI key	IBOVDNBDQHYNJI-QZQOTICOSA-N
Quality Level	100
SMILES string	CN(C)c1ccc(cc1)N=Nc2ccc(cc2)C(=O)ON3C(=O)CCC3=O
solubility	DMF: soluble
	DMSO: soluble
storage temp.	−20°C

Analysis Note:	Absorption spectra shows a maximum at 453 nm (in methanol). After reaction with butylamine: max. absorption at 428 nm (Lit.)
Application:	A useful reagent (similar to MANCYL-SE) for labeling proteins or peptides through their amino-groups by forming stable peptide bonds. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles for fluorescent studies of proteins. Its fluorescent properties (has a characteristic broad and intense visible absorption but has no fluorescence) make it an ideal long wavelength quencher and it has been utilized as an acceptor chromophore in FRET studies.
Other Notes:	N-terminal modification of peptides in automated synthesis

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98.0% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352108