Human Dermal Microvascular Endothelial Cells: CADMEC/HMVEC, neonatal
SIGMA/100-05N
Product Type: Product-on-demand
biological source | human neonatal foreskin or adult skin capillaries (normal) |
growth mode | Adherent |
karyotype | 2n = 46 |
manufacturer/tradename | Cell Applications, Inc |
morphology | Endothelial |
packaging | pkg of 500,000 cells |
Quality Level | 100 |
shipped in | dry ice |
storage temp. | −196°C |
technique(s) | cell culture | mammalian: suitable |
Application: | Endothelial vessel function, cell signaling, angiogenesis |
Cell Line Origin: | Skin |
Components: | Cell Basal Medium containing 10% FBS & 10% DMSO |
Disclaimer: | RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization. |
General description: | Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details. CADMEC/HMVEC provide an excellent model system to study many aspects of endothelial function and disease, especially those related to the microvasculature and capillary systems. HMVEC/CADMEC have been shown to express vWF, CD36 and CD31, are able to uptake DiI-Ac-LDL and are positive for functional activity by cytokine-stimulated leukocyte adherence. Select HMVEC lots have been additionally tested to demonstrate stimulation-dependent angiogenesis and key endothelial cell signaling pathways (phosphorylation of VEGFR, Akt, MAPK, and expression of Tie2, eNOS, Axl and Etk/Bmx). |
Preparation Note: | • 2nd passage, >500,000 cells in Cell Basal Medium containing 10% FBS & 10% DMSO • Can be cultured at least 16 doublings |
Subculture Routine: | Please refer to the CADMEC/HMVEC Culture Protocol . |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −196°C |
UNSPSC | 41106514 |