Angiotensin III trifluoroacetate salt hydrate

SIGMA/10385 - ≥98% (HPCE)

Synonym: Des-Asp-1-Angiotensin II trifluoroacetate salt hydrate

CAS Number: 12687-51-3 (free base)
Empirical Formula (Hill Notation): C₄₆H₆₆N₁₂O₉ · xC₂HF₃O₂ · yH₂O
Molecular Weight: 931.09 (anhydrous free base basis)
MDL Number: MFCD20264812
Linear Formula: C₄₆H₆₆N₁₂O₉ · xC₂HF₃O₂ · yH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-10385-5MG	5 mg	$91.60 1/EA	Add To Favorites
45-10385-25MG	25 mg	$334.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPCE)
InChI	1S/C46H66N12O9.C2HF3O2.H2O/c1-5-27(4)38(57-40(61)33(21-29-15-17-31(59)18-16-29)53-42(63)37(26(2)3)56-39(60)32(47)13-9-19-51-46(48)49)43(64)54-34(23-30-24-50-25-52-30)44(65)58-20-10-14-36(58)41(62)55-35(45(66)67)22-28-11-7-6-8-12-28;3-2(4,5)1(6)7;/h6-8,11-12,15-18,24-27,32-38,59H,5,9-10,13-14,19-23,47H2,1-4H3,(H,50,52)(H,53,63)(H,54,64)(H,55,62)(H,56,60)(H,57,61)(H,66,67)(H4,48,49,51);(H,6,7);1H2/t27-,32-,33-,34-,35-,36-,37-,38-;;/m0../s1
InChI key	JEOAJMGVSAMVML-UFPGTABSSA-N
Quality Level	100
SMILES string	O.OC(=O)C(F)(F)F.CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(N)=N)C(C)C)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](Cc4ccccc4)C(O)=O
solubility	H₂O: 1.0 mg/mL, clear, colorless
storage temp.	−20°C

Amino Acid Sequence:	Arg-Val-Tyr-Ile-His-Pro-Phe
Antibody Adsorbant:	Arg-Val-Tyr-Ile-His-Pro-Phe-OH.3CH₃COOH.4H₂O
Biochem/physiol Actions:	Angiotensin III is an AT₁ and AT₂ agonist, with higher sensitivity for the AT₂ receptor. Ang III has been shown to be a main effector peptide in RAS-controlled vasopresin release and a stimulator for aldosterone release.
Features and Benefits:	This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description:	Angiotensin III (Ang III) is a 7-AA bioactive peptide that is formed from the degradation of the Angiotensin II peptide by aminopeptidase A; both are derivatives of angiotensinogen and are components of the renin-angiotensin system (RAS).
Other Notes:	Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 10385.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPCE)
Storage Temp.	−20°C
UNSPSC	12352200

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