Angiotensin III trifluoroacetate salt hydrate

SIGMA/10385 - ≥98% (HPCE)

Synonym: Des-Asp-1-Angiotensin II trifluoroacetate salt hydrate

CAS Number: 12687-51-3 (free base)
Empirical Formula (Hill Notation): C₄₆H₆₆N₁₂O₉ · xC₂HF₃O₂ · yH₂O
Molecular Weight: 931.09 (anhydrous free base basis)
MDL Number: MFCD20264812
Linear Formula: C₄₆H₆₆N₁₂O₉ · xC₂HF₃O₂ · yH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-10385-5MG	5 mg	$94.20 1/EAAdd To Favorites	Add To Favorites
45-10385-25MG	25 mg	$343.00 1/EAAdd To Favorites	Add To Favorites

assay	≥98% (HPCE)
InChI	1S/C46H66N12O9.C2HF3O2.H2O/c1-5-27(4)38(57-40(61)33(21-29-15-17-31(59)18-16-29)53-42(63)37(26(2)3)56-39(60)32(47)13-9-19-51-46(48)49)43(64)54-34(23-30-24-50-25-52-30)44(65)58-20-10-14-36(58)41(62)55-35(45(66)67)22-28-11-7-6-8-12-28;3-2(4,5)1(6)7;/h6-8,11-12,15-18,24-27,32-38,59H,5,9-10,13-14,19-23,47H2,1-4H3,(H,50,52)(H,53,63)(H,54,64)(H,55,62)(H,56,60)(H,57,61)(H,66,67)(H4,48,49,51);(H,6,7);1H2/t27-,32-,33-,34-,35-,36-,37-,38-;;/m0../s1
InChI key	JEOAJMGVSAMVML-UFPGTABSSA-N
Quality Level	100
SMILES string	O.OC(=O)C(F)(F)F.CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(N)=N)C(C)C)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](Cc4ccccc4)C(O)=O
solubility	H₂O: 1.0 mg/mL, clear, colorless
storage temp.	−20°C

Amino Acid Sequence:	Arg-Val-Tyr-Ile-His-Pro-Phe
Antibody Adsorbant:	Arg-Val-Tyr-Ile-His-Pro-Phe-OH.3CH₃COOH.4H₂O
Biochem/physiol Actions:	Angiotensin III is an AT₁ and AT₂ agonist, with higher sensitivity for the AT₂ receptor. Ang III has been shown to be a main effector peptide in RAS-controlled vasopresin release and a stimulator for aldosterone release.
Features and Benefits:	This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description:	Angiotensin III (Ang III) is a 7-AA bioactive peptide that is formed from the degradation of the Angiotensin II peptide by aminopeptidase A; both are derivatives of angiotensinogen and are components of the renin-angiotensin system (RAS).

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPCE)
Storage Temp.	−20°C
UNSPSC	12352200