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CD7 (MRQ-56) Mouse Monoclonal Antibody

SIGMA/107M-2

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-107M-24 0.1 mL
$0.00
1/EA
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45-107M-25 0.5 mL
$0.00
1/EA
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45-107M-26 1 mL
$0.00
1/EA
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45-107M-27 1 mL
$0.00
1/EA
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45-107M-28 7 mL
$0.00
1/EA
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Immunohistochemistry CD7 (MRQ-56) on tonsil

 

antibody form culture supernatant
antibody product type primary antibodies
biological source mouse
clone MRQ-56, monoclonal
conjugate unconjugated
control lymph node, peripheral T-cell lymphoma, tonsil
description For In Vitro Diagnostic Use in Select Regions (See Chart)
form buffered aqueous solution
isotype IgG1
manufacturer/tradename Cell Marque
packaging bottle of 1.0 mL predilute (107M-27)
  bottle of 7.0 mL predilute (107M-28)
  vial of 0.1 mL concentrate (107M-24)
  vial of 0.5 mL concentrate (107M-25)
  vial of 1.0 mL concentrate (107M-26)
Quality Level 100 
  500 
shipped in wet ice
species reactivity human
storage temp. 2-8°C
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
visualization membranous
General description: CD7 antigen is a cell surface glycoprotein of 40 kD expressed on the surface of immature and mature T-cells as well as natural Killer (NK) cells. It is a member of the immunoglobulin gene superfamily and is the first T-cell lineage associated antigen to appear in T-cell ontogeny, being expressed in T-cell precursors (preceding CD2 expression), and in myeloid precursors, in fetal liver and bone marrow, and persisting in circulating mature T-cells. While its precise function is not known, it is suggested that the molecule functions as an Fc receptor for IgM. CD7 is the most consistently expressed T-cell antigen in lymphoblastic lymphomas/leukemias, and is therefore anti-CD7 is a useful marker in the identification of such neoplastic proliferations. In mature post-thymic T-cell neoplasms, CD7 is the most common pan-T-antigen to be aberrantly expressed, which is a useful pointer to a neoplastic T-cell process. CD7 has been shown to be immunoexpressed in 85% of mature peripheral T-cells, the majority of post-thymic T-cells, NK cells, T-cell lymphoblastic leukemia/lymphoma, acute myeloid leukemia, and chronic myelogenous leukemia, CD7 is conspicuously absent in adult T-cell leukemia/lymphoma and is not expressed in mycosis fungoides.
Legal Information: Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
Linkage: CD7 Positive Control Slides, Product No. 107S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Other Notes: For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Physical form: Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note: Download the IFU specific to your product lot and format Note: This requires a keycode which can be found on your packaging or product label.
Quality:

IVD

IVD

IVD

RUO
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 12352200

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