L-Arginine monohydrochloride

SIGMA/11039 - BioUltra, ≥99.5% (AT)

Synonym: (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride; (S)-(+)-Arginine hydrochloride

CAS Number: 1119-34-2
Empirical Formula (Hill Notation): C₆H₁₄N₄O₂ · HCl
Molecular Weight: 210.66
EC Number: 214-275-1
MDL Number: MFCD00064550
Linear Formula: C₆H₁₄N₄O₂ · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-11039-100G	100 g	$111.00 1/EAAdd To Favorites	Add To Favorites
45-11039-500G	500 g	$388.00 1/EAAdd To Favorites	Add To Favorites

λ	1 M in H₂O
anion traces	sulfate (SO₄^2-): ≤50 mg/kg
assay	≥99.5% (AT)
cation traces	Al: ≤5 mg/kg
	As: ≤0.1 mg/kg
	Ba: ≤5 mg/kg
	Bi: ≤5 mg/kg
	Ca: ≤10 mg/kg
	Cd: ≤5 mg/kg
	Co: ≤5 mg/kg
	Cr: ≤5 mg/kg
	Cu: ≤5 mg/kg
	Fe: ≤5 mg/kg
	K: ≤50 mg/kg
	Li: ≤5 mg/kg
	Mg: ≤5 mg/kg
	Mn: ≤5 mg/kg
	Mo: ≤5 mg/kg
	Na: ≤50 mg/kg
	Ni: ≤5 mg/kg
	Pb: ≤5 mg/kg
	Sr: ≤5 mg/kg
	Zn: ≤5 mg/kg
color	colorless
density	1.42 g/cm³ at 20 °C
form	powder or crystals
ign. residue	≤0.05%
impurities	insoluble matter, passes filter test
	≤0.3% foreign amino acids
InChI	1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1
InChI key	KWTQSFXGGICVPE-WCCKRBBISA-N
loss	≤0.05% loss on drying, 20 °C (HV)
mp	220-230 °C
optical activity	[α]20/D +22.0±0.5°, c = 5% in 5 M HCl
pH	5.5-7.0 (25 °C, 1 M in H₂O)
product line	BioUltra
Quality Level	200
SMILES string	Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O
solubility	H₂O: 1 M at 20 °C, clear, colorless
technique(s)	ligand binding assay: suitable
UV absorption	λ: 260 nm A_max: ≤0.2
	λ: 280 nm A_max: ≤0.1

Application:	L-Arginine monohydrochloride has been used to study the reversal of the inhibitory effect of L-N^G0-nitroarginine on non-cholinergic relaxations. It has also been used as a dietary supplement to study its effect on endothelium-dependent vasodilation.
Biochem/physiol Actions:	L-Arginine is considered as a semi essential amino acid. In most mammals including humans, L-Arginine synthesis occurs through intestinal-renal axis, from glutamine, glutamate and proline. Abnormal levels of L-Arginine is associated with the development of kidney and cardiovascular disease. L-arginine is found to decrease fat mass and visceral adiposity.
Biochem/physiol Actions:	Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99.5% (AT)
mp	220-230 °C
Density	1.42 g/cm³ at 20 °C
UNSPSC	12352209