CD11c (EP157) Rabbit Monoclonal Primary Antibody
SIGMA/111R-1
Product Type: Chemical
Immunohistochemistry CD11c (EP157) on Hairy Cell Leukemia
| antibody form | culture supernatant |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | EP157, monoclonal |
| conjugate | unconjugated |
| control | hairy cell leukemia, spleen, tonsil |
| description | For In Vitro Diagnostic Use in Select Regions |
| form | buffered aqueous solution |
| isotype | IgG |
| manufacturer/tradename | Cell Marque™ |
| packaging | vial of 0.1 mL concentrate (111R-14) |
| vial of 0.1 mL concentrate Research Use Only (111R-14-RUO) | |
| vial of 0.5 mL concentrate (111R-15) | |
| vial of 1.0 mL concentrate (111R-16) | |
| vial of 1.0 mL concentrate Research Use Only (111R-16-RUO) | |
| vial of 1.0 mL pre-dilute ready-to-use (111R-17) | |
| vial of 1.0 mL pre-dilute Research Use Only (111R-17-RUO) | |
| vial of 7.0 mL pre-dilute ready-to-use (111R-18) | |
| vial of 7.0 mL pre-dilute ready-to-use Research Use Only (111R-18-RUO) | |
| Quality Level | 100  |
| 500 |
|
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated) |
| visualization | cytoplasmic |
| General description: | CD11c is an adhesion receptor of the leukocyte function-associated family of molecules. This cell surface antigen is normally expressed on granulocytes, monocytes, natural killer cells, macrophages, and small populations of T- and B-lymphocytes. Anti-CD11c detects a formalin-resistant epitope of CD11c expressed in hairy cell leukemia (HCL). HCL is a distinctive yet uncommon chronic B-cell lymphoproliferative disorder, predominantly involving the bone marrow and spleen. Besides being consistently expressed in HCL, CD11c is rarely detected in lymphomas; such as small lymphocytic lymphoma (SLL), and nodal and extranodal marginal zone lymphoma (MZL). | ||||
| Legal Information: | Cell Marque is a trademark of Sigma-Aldrich Co. LLC | ||||
| Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
| Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide. | ||||
| Preparation Note: | Download the IFU specific to your product lot and format  Note: This requires a keycode which can be found on your packaging or product label. Download the latest released IFU Note: This IFU may not apply to your specific product lot. |
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| Quality: |
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| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |