CD13 (EP117) Rabbit Monoclonal Primary Antibody
SIGMA/113R-2
Synonym: Aminopeptidase-N
Product Type: Chemical
Immunohistochemistry CD13 (EP117) on bone marrow
| antibody form | culture supernatant |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | EP117, monoclonal |
| concentration | 0.1-5 μg/mL (predilute) |
| 2.5-125 μg/mL (concentrate) | |
| conjugate | unconjugated |
| control | liver |
| description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| form | buffered aqueous solution |
| isotype | IgG |
| manufacturer/tradename | Cell Marque™ |
| packaging | vial of 0.1 mL concentrate (113R-24) |
| vial of 0.1 mL concentrate Research Use Only (113R-24-RUO) | |
| vial of 0.5 mL concentrate (113R-25) | |
| vial of 1.0 mL concentrate (113R-26) | |
| vial of 1.0 mL concentrate Research Use Only (113R-26-RUO) | |
| vial of 1.0 mL pre-dilute ready-to-use (113R-27) | |
| vial of 1.0 mL pre-dilute Research Use Only (113R-27-RUO) | |
| vial of 7.0 mL pre-dilute ready-to-use (113R-28) | |
| vial of 7.0 mL pre-dilute ready-to-use Research Use Only (113R-28-RUO) | |
| Quality Level | 100  |
| 500 |
|
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated) |
| visualization | cytoplasmic, membranous |
| General description: | CD13 (aminopeptidase-N) is a transmembrane protease present in many tissues and cell types (e.g., endothelial and epithelial cells, fibroblasts, and leukocytes). CD13 is expressed in various solid and hematological malignancies in humans and is useful in identifying acute myeloid leukemia when used in a panel including antibodies against CD13(+), CD34(+), CD117(+), CD16(-), and CD33(+). This protein is also expressed in myeloid sarcoma and anti-CD13 is useful in its identification using a panel. In addition, it has been reported that CD13 is expressed in both normal and neoplastic liver tissue, where it exhibits a canalicular distribution pattern similar to that seen for polyclonal CEA and CD10. Thus, anti-CD13 can be useful as an additional marker in differentiating between HCC and non-hepatocellular neoplasms. |
| Legal Information: | Cell Marque is a trademark of Sigma-Aldrich Co. LLC |
| Linkage: | CD13 Positive Control Slides, Product No. 113S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). |
| Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com |
| Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Preparation Note: | Download the IFU specific to your product lot and format  Note: This requires a keycode which can be found on your packaging or product label. Download the latest released IFU Note: This IFU may not apply to your specific product lot. |
| Quality: | United States - IVD Canada - IVD European Union - IVD Japan - RUO |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |