Bafilomycin B1 from Streptomyces sp.
SIGMA/11707 - ≥80% (HPLC)
Synonym: Setamycin
CAS Number: 88899-56-3
Empirical Formula (Hill Notation): C44H65NO13
Molecular Weight: 815.99
Linear Formula: C44H65NO13
Product Type: Chemical
antibiotic activity spectrum | fungi |
Gram-positive bacteria | |
assay | ≥80% (HPLC) |
color | white to yellow |
form | powder or crystals |
InChI | 1S/C44H65NO13/c1-23(2)41- |
InChI key | KFUFLYSBMNNJTF-HHZDOKBSSA |
mode of action | enzyme | inhibits |
Quality Level | 200 |
shipped in | wet ice |
SMILES string | CO[C@H]1C=CC=C(C)C[C@H] |
storage temp. | −20°C |
Application: | Bafilomycin B1 is a toxic macrolide antibiotic used to study cell processes such as autophagy, pH control within cells, and mechanisms of apoptosis . |
Biochem/physiol Actions: | Bafilomycin B1 inhibits vacuolar type H+-ATPase (V-ATPase) and is used to study cell processes such as autophagy, pH control within cells, and mechanisms of apoptosis. |
Biochem/physiol Actions: | Bafilomycin B1 inhibits vacuolar type H+-ATPase (V-ATPase). Bafilomycin B1′s activity results from the presence of a large macrocyclic lactone ring to which deoxy sugars may attach. |
General description: | Chemical structure: macrolide |
Other Notes: | Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Moisture sensitive. Keep in a dry place. |
Packaging: | 1MG |
Warning: | Fatal if swallowed. Bafilomycin B1 is fatal if it is inhaled, swallowed, or if it comes in contact with skin. |
Symbol | GHS06 |
Signal word | Danger |
Hazard statements | H300 + H310 + H330 |
Precautionary statements | P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310 |
Hazard Codes | T+ |
Risk Statements | 26/27/28 |
Safety Statements | 36/37/39-45 |
RIDADR | UN 3462 6.1 / PGI |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥80% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 51101500 |