CD23 (MRQ-57) Mouse Monoclonal Antibody

SIGMA/123M-2

Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-123M-24	0.1 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-123M-25	0.5 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-123M-26	1 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-123M-27	1 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-123M-28	7 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites

Immunohistochemistry CD23 (MRQ-57) on marginal zone lymphoma

antibody form	culture supernatant
antibody product type	primary antibodies
biological source	mouse
clone	MRQ-57, monoclonal
conjugate	unconjugated
control	chronic lymphocytic leukemia, lymph node, small lymphocytic lymphoma, tonsil
description	For In Vitro Diagnostic Use in Select Regions (See Chart)
form	buffered aqueous solution
isotype	IgG2a
manufacturer/tradename	Cell Marque^™
packaging	bottle of 1.0 mL predilute (123M-27)
	bottle of 7.0 mL predilute (123M-28)
	vial of 0.1 mL concentrate (123M-24)
	vial of 0.5 mL concentrate (123M-25)
	vial of 1.0 mL concentrate (123M-26)
Quality Level	100
	500
shipped in	wet ice
species reactivity	human
storage temp.	2-8°C
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
visualization	membranous

General description:

CD23 antigen is a 45-60 kDa membrane glycoprotein identified as a low affinity receptor for IgE production as well as a receptor for lymphocyte growth factor. CD23 is found in some mature B-cell lymphomas and in Reed-Sternberg cells in Hodgkin disease. Follicular dendritic cells and some activated B-cells within germinal centers express CD23 in high density and mantle zone B-cells are stained weakly.The majority of chronic lymphocytic leukemias/small lymphocytic lymphomas are CD23 positive, whereas mantle cell lymphomas are generally negative, so this marker is useful when applied with other markers to separate the small cell lymphomas.Precursor B and T lymphomas, myeloid neoplasms, and mature T-cell lymphomas are CD23 negative and other small cell lymphomas are occasionally positive.CD23 is also positive on activated mature B-cells expressing IgM or IgD, monocytes/macrophages, follicular dendritic cells, T-cell subsets, eosinophils, Langerhans cells and B-cell Chronic lymphocytic leukemia/Small lymphocytic lymphoma (CLL/SLL).

Legal Information:

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Linkage:

CD23 Positive Control Slides, Product No. 123S External link

, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes:

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form:

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note:

Download the IFU specific to your product lot and format External link

Note: This requires a keycode which can be found on your packaging or product label.

Quality:

IVD

RUO

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-8°C
UNSPSC	12352203