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1,4-Bis(acryloyl)piperazine

SIGMA/14470 - BioXtra, suitable for electrophoresis, ≥99.0% (TLC)

Synonym: 1,4-Di(acryloyl)piperazine; N,N′-Bis(acryloyl)piperazine; BAP; PDA; Piperazine diacrylamide

CAS Number: 6342-17-2
Empirical Formula (Hill Notation): C10H14N2O2
Molecular Weight: 194.23
MDL Number: MFCD00077661
Linear Formula: C10H14N2O2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-14470-5G-F 5 g
$297.00
1/EA
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45-14470-25G-F 25 g
$1190.00
1/EA
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anion traces chloride (Cl-): ≤200 mg/kg
  sulfate (SO42-): ≤50 mg/kg
assay ≥99.0% (TLC)
cation traces Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg
form solid
impurities ≤0.05% free acrylic acid
InChI 1S/C10H14N2O2/c1-3-9(13)11-5-7-12(8-6-11)10(14)4-2/h3-4H,1-2,5-8H2
InChI key YERHJBPPDGHCRJ-UHFFFAOYSA-N
mp 91.5-93.5 °C (lit.)
product line BioXtra
Quality Level 100 
SMILES string C=CC(=O)N1CCN(CC1)C(=O)C=C
storage temp. 2-8°C
suitability suitable for electrophoresis
technique(s) electrophoresis: suitable
Application:

  • Fabrication and application of zwitterionic phosphorylcholine functionalized monoliths with different hydrophilic crosslinkers in hydrophilic interaction chromatography: This study demonstrates the effective use of 1,4-Bis(acryloyl)piperazine as a crosslinker in creating zwitterionic monoliths for chromatographic applications, highlighting its utility in enhancing polymer interactions and selectivity in separation processes (Wang et al., 2020 ).

  • Poly(amidoamine) conjugates with disulfide-linked cholesterol pendants self-assembling into redox-sensitive nanoparticles: This application uses a derivative concept where 1,4-Bis(acryloyl)piperazine could theoretically enhance the self-assembly and stability of redox-sensitive polymeric nanoparticles, offering insights into controlled release and targeted drug delivery systems (Ranucci et al., 2008 ).

Other Notes: Used as a vinylating agent for graft-copolymerization of different enzymes to cellulose, dextran, or starch; New crosslinking agent for polyacrylamide gels with improved protein separation and detection by silver staining; Increased resolution in 2D-protein electrophoresis.
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H315 - H319 - H335
Precautionary statements P261 - P305 + P351 + P338
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99.0% (TLC)
mp 91.5-93.5 °C (lit.)
Storage Temp. 2-8°C
UNSPSC 41105319

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