1,4-Bis(acryloyl)piperazine

SIGMA/14470 - BioXtra, suitable for electrophoresis, ≥99.0% (TLC)

Synonym: 1,4-Di(acryloyl)piperazine; N,N′-Bis(acryloyl)piperazine; BAP; PDA; Piperazine diacrylamide

CAS Number: 6342-17-2
Empirical Formula (Hill Notation): C₁₀H₁₄N₂O₂
Molecular Weight: 194.23
MDL Number: MFCD00077661
Linear Formula: C₁₀H₁₄N₂O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-14470-5G-F	5 g	$297.00 1/EA	Add To Favorites
45-14470-25G-F	25 g	$1190.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

anion traces	chloride (Cl^-): ≤200 mg/kg
	sulfate (SO₄^2-): ≤50 mg/kg
assay	≥99.0% (TLC)
cation traces	Ca: ≤10 mg/kg
	Cd: ≤5 mg/kg
	Co: ≤5 mg/kg
	Cr: ≤5 mg/kg
	Cu: ≤5 mg/kg
	Fe: ≤5 mg/kg
	K: ≤50 mg/kg
	Mg: ≤5 mg/kg
	Mn: ≤5 mg/kg
	Na: ≤50 mg/kg
	Ni: ≤5 mg/kg
	Pb: ≤5 mg/kg
	Zn: ≤5 mg/kg
form	solid
impurities	≤0.05% free acrylic acid
InChI	1S/C10H14N2O2/c1-3-9(13)11-5-7-12(8-6-11)10(14)4-2/h3-4H,1-2,5-8H2
InChI key	YERHJBPPDGHCRJ-UHFFFAOYSA-N
mp	91.5-93.5 °C (lit.)
product line	BioXtra
Quality Level	100
SMILES string	C=CC(=O)N1CCN(CC1)C(=O)C=C
storage temp.	2-8°C
suitability	suitable for electrophoresis
technique(s)	electrophoresis: suitable

Application:

Fabrication and application of zwitterionic phosphorylcholine functionalized monoliths with different hydrophilic crosslinkers in hydrophilic interaction chromatography: This study demonstrates the effective use of 1,4-Bis(acryloyl)piperazine as a crosslinker in creating zwitterionic monoliths for chromatographic applications, highlighting its utility in enhancing polymer interactions and selectivity in separation processes (Wang et al., 2020 ).

Poly(amidoamine) conjugates with disulfide-linked cholesterol pendants self-assembling into redox-sensitive nanoparticles: This application uses a derivative concept where 1,4-Bis(acryloyl)piperazine could theoretically enhance the self-assembly and stability of redox-sensitive polymeric nanoparticles, offering insights into controlled release and targeted drug delivery systems (Ranucci et al., 2008 ).

Other Notes:

Used as a vinylating agent for graft-copolymerization of different enzymes to cellulose, dextran, or starch; New crosslinking agent for polyacrylamide gels with improved protein separation and detection by silver staining; Increased resolution in 2D-protein electrophoresis.

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P261 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99.0% (TLC)
mp	91.5-93.5 °C (lit.)
Storage Temp.	2-8°C
UNSPSC	41105319

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