Phalloidin-Atto 490LS

SIGMA/14479 - suitable for fluorescence

Synonym: Atto 490LS-Phalloidin

Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-14479-10NMOL	10 nmol	$609.00 1/EAAdd To Favorites	Add To Favorites

λ	in acetonitrile: water (1:1)
assay	≥75.0% (HPLC)
manufacturer/tradename	ATTO-TEC GmbH
mol wt	M_w 1466 g/mol
Quality Level	100
storage temp.	−20°C
suitability	suitable for fluorescence
UV absorption	λ: 495-501 nm A_max

General description:

Atto 490LS is a new fluorescent label featuring an extraordinary large Stokes-Shift of 165 nm. Thus the emission spectrum is almost completely separated from its absorption spectrum, making the dye highly suitable for multiplexing experiments, in particular in combination with Atto 488 and Atto 514. Atto 490LS is very hydrophillic and shows excellent water solubility. The dye exhibits a relatively high fluorescence quantum yield, which is only slightly reduced after conjugation to biomolecules, e.g. proteins, even at high degrees of labeling (DOL). Atto 490LS is an anionic dye. After conjugation to a substrate the dye carries a net electrical charge of ^-1.
Phalloidin, a bicyclic heptapeptide, is a very strong binding reagent to actin. Fluorescent labeled phalloidin has become a useful tool to investigate the distribution of F-actin within the cytoskeleton of cells by fluorescence microscopy.

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Legal Information:

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥75.0% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352108