Synonym: 2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol; 2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol; Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane
CAS Number: 6976-37-0
Empirical Formula (Hill Notation): C8H19NO5
Molecular Weight: 209.24
EC Number: 230-237-7
MDL Number: MFCD00002853
Linear Formula: C8H19NO5
Product Type: Chemical
| λ |
1 M in H2O |
| absorption |
cut-off at 270 nm in H2O at 1 M |
| anion traces |
chloride (Cl-): ≤50 mg/kg |
| |
sulfate (SO42-): ≤50 mg/kg |
| assay |
≥99.0% (NT) |
| cation traces |
Al: ≤5 mg/kg |
| |
As: ≤0.1 mg/kg |
| |
Ba: ≤5 mg/kg |
| |
Bi: ≤5 mg/kg |
| |
Ca: ≤10 mg/kg |
| |
Cd: ≤5 mg/kg |
| |
Co: ≤5 mg/kg |
| |
Cr: ≤5 mg/kg |
| |
Cu: ≤5 mg/kg |
| |
Fe: ≤5 mg/kg |
| |
K: ≤50 mg/kg |
| |
Li: ≤5 mg/kg |
| |
Mg: ≤5 mg/kg |
| |
Mn: ≤5 mg/kg |
| |
Mo: ≤5 mg/kg |
| |
Na: ≤50 mg/kg |
| |
Ni: ≤5 mg/kg |
| |
Pb: ≤5 mg/kg |
| |
Sr: ≤5 mg/kg |
| |
Zn: ≤5 mg/kg |
| form |
powder |
| ign. residue |
≤0.3% |
| impurities |
insoluble matter, passes filter test |
| InChI |
1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2 |
| InChI key |
OWMVSZAMULFTJU-UHFFFAOYSA-N |
| loss |
≤0.5% loss on drying, 20 °C (HV) |
| pH |
9.5-11.0 (25 °C, 1 M in H2O) |
| pKa (25 °C) |
6.5 |
| product line |
BioUltra |
| Quality Level |
200  |
| SMILES string |
OCCN(CCO)C(CO)(CO)CO |
| solubility |
H2O: 1 M at 20 °C, clear, colorless |
| useful pH range |
5.8-7.2 |
| UV absorption |
λ: 280 nm Amax: 0.15 |
| Application: |
BIS-TRIS can be used to study biological buffers. BIS-TRIS has been used in a study that synthesized ferritin grafted with temperature-responsive poly(N-isopropylacrylamide) (PIPAAm-ferritin) by a coupling reaction using PIPAAm and ferritin for obtaining stimuli-responsive biomaterials. BIS-TRIS has also been used in a study that synthesized and described the photochemical properties of oligo- ortho –azobenzenes. |
| Other Notes: |
Easily compare specifications for BIS-TRIS products with the BIS-TRIS specification table . |
| Other Notes: |
Effective buffer for the assay of creatine kinase; Effectively protects hemoglobin during freeze-drying; Catholyte in IEF of 2-D gel electrophoresis. |
| Symbol |
 GHS05 |
| Signal word |
Danger |
| Hazard statements |
H318 |
| Precautionary statements |
P280 - P305 + P351 + P338 + P310 |
| Hazard Codes |
Xi |
| Risk Statements |
36/37/38 |
| Safety Statements |
26-36 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 2 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥99.0% (NT) |
| UNSPSC |
12161700 |
