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Poloxamer 188

SIGMA/15759

Synonym: Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol); Lutrol F68

CAS Number: 9003-11-6
MDL Number: MFCD00082049
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-15759-1KG 1 kg
 $144.00
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CMC 0.48 mM
color APHA: ≤120, 50/50 in CH3OH
composition oxyethylene, 79.9-83.7%
form solid
HLB >24
ign. residue ≤0.30%
impurities ≤0.25% ethylene glycol and diethylene glycol
  ≤0.4% total ash
  ≤1 ppm ethylene oxide
  ≤1.0% water
  ≤2 ppm arsenic traces
  ≤20 ppm heavy metals
  ≤5 ppm dioxan
  ≤5 ppm propylene oxide
  50-150 ppm butylhydroxytoluene
InChI 1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key RVGRUAULSDPKGF-UHFFFAOYSA-N
mol wt ~7680-9510 g/mol
pH 5.0-7.5 (100 g/L in H2O)
  6.0-7.5 (25 g/L in H2O)
Quality Level 200 
SMILES string O2C(C2)C.O1CC1
transition temp cloud point >100 °C
Application:

  • Stabilizing Function of P 188 in Dermal Formulations: Examined for its stabilizing effects on industrial concentrates of dermal hesperidin smartCrystals, P 188 contributed to enhancing the long-term stability of the formulations, relevant for dermal therapeutic interventions (Romero et al., 2015 ).
Biochem/physiol Actions: Poloxamer 188 is widely used as a thickening agent and gel binder.
Other Notes: The Poloxamer 188 grades are poloxamers from the extensive line of block copolymers.
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 12352104

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