Advanced Search



CD57 (NK-1) Mouse Monoclonal Antibody

SIGMA/157M-9

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-157M-94 0.1 mL
$0.00
1/EA
CALL FOR PRICE
Add To Favorites
45-157M-95 0.5 mL
$0.00
1/EA
CALL FOR PRICE
Add To Favorites
45-157M-96 1 mL
$0.00
1/EA
CALL FOR PRICE
Add To Favorites
45-157M-97 1 mL
$0.00
1/EA
CALL FOR PRICE
Add To Favorites
45-157M-98 7 mL
$0.00
1/EA
CALL FOR PRICE
Add To Favorites
Immunohistochemistry CD57 (NK-1) on tonsil

 

antibody form diluted ascites fluid
antibody product type primary antibodies
biological source mouse
clone NK-1, monoclonal
conjugate unconjugated
control tonsil
description For In Vitro Diagnostic Use in Select Regions (See Chart)
form buffered aqueous solution
isotype IgMκ
manufacturer/tradename Cell Marque
packaging bottle of 1.0 mL predilute (157M-97)
  bottle of 7.0 mL predilute (157M-98)
  vial of 0.1 mL concentrate (157M-94)
  vial of 0.5 mL concentrate (157M-95)
  vial of 1.0 mL concentrate (157M-96)
Quality Level 100 
  500 
shipped in wet ice
species reactivity human
storage temp. 2-8°C
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
visualization membranous
General description: CD57 is a marker expressed in the membrane of NK cells and other T cells. It is often used in the identification of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) to visualize the small T-cells that ring the LP cells (rosettes of follicular T cells around the large neoplastic LP cells). These features can be used to distinguish NLPHL from T-cell/histiocyte-rich large B-cell lymphoma, which usually shows no rosettes of CD57-positive follicular T-cells around the large tumor cells. Anti-CD57 also reacts with neuroendocrine cells and their derived tumors, including neuroendocrine tumors of diverse origins, pheochromocytomas, paragangliomas, medulloblastoma, and varying proportions of neural tumors such as schwannomas, neurofibromas, neuromas, and granular cell tumors. However, anti-CD57 lacks the specificity of chromogranin and synaptophysin for detecting neuroendocrine neoplasms and therefore should be considered in a panel. Anti-CD57 can also be useful in separating thymoma from thymic carcinoma when combined with a panel that includes antibodies against CD5 and CD117.
General description: CD57, also known as HNK-1 (human natural killer-1), is a cell surface carbohydrate epitope expressed on terminally differentiated T-cells and subsets of natural killer (NK) cells. It has also been identified in cells of neural crest origin. CD57 antibodies are often used to visualize non-neoplastic bystander T-cells. These T-cells have been known to form rosettes around neoplastic lymphocyte-predominant (LP) cells in nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL).
Legal Information: Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
Linkage: CD57 Positive Control Slides, Product No. 157S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Other Notes: For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Physical form: Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note: Download the IFU specific to your product lot and format Note: This requires a keycode which can be found on your packaging or product label.
Quality:

IVD

IVD

IVD

RUO
RIDADR NONH for all modes of transport
Storage Temp. 2-8°C
UNSPSC 12352200

The following items have been added to your cart:

Choose a favorite list for this item:

Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Year Price Updates

We are currently working diligently to update our website pricing information for the New Year. If you place an order, you will be acknowledged with any corrected pricing. If you'd like the most current information sooner, please don't hesitate to drop us an email or give us a call and we'd be happy to assist. Thank you for your patience while we are updating.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top