Sodium (S)-β-hydroxyisobutyrate

SIGMA/16842 - ≥96.0%

Synonym: (S)-β-Hydroxy-isobutyric acid sodium salt; (S)-3-Hydroxy-2-methylpropionic acid sodium salt; S-HIBA; R-β-HIBA-Na; Sodium (S)-3-hydroxy-2-methylpropionate

CAS Number: 1893416-17-5; 26543-05-5 (free acid)
Empirical Formula (Hill Notation): C₄H₇NaO₃
Molecular Weight: 126.09
MDL Number: MFCD17215930
Linear Formula: C₄H₇NaO₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-16842-100MG	100 mg	$249.00 1/EAAdd To Favorites	Add To Favorites

assay	≥96.0%
	≥96.0% (GC)
composition	sodium, 17.5-19.0%
InChI	1S/C4H8O3.Na/c1-3(2-5)4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1/t3-;/m0./s1
InChI key	RBJZIQZDAZLXEK-DFWYDOINSA-M
optical purity	enantiomeric excess: ≥98.0%
Quality Level	100
SMILES string	[Na+].C[C@@H](CO)C([O-])=O
storage temp.	2-8°C

Application:	3-Hydroxyisobutyrate (HIBA) may be used to study the distribution, characterization and kinetics of enzymes involved in branched chain amino acid metabolism such as 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4). (S)-β-hydroxyisobutyrate may be used in stereospecific studies.
Biochem/physiol Actions:	Metabolite in valine, leucine and isoleucine degradation, a reactant of enzymes 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31), 3-hydroxyacyl-CoA dehydrogenase (EC: 1.1.1.35) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4). Enantiomeric ratio can be used in diagnosis of metabolic diseases, e.g. 3-hydroxyisobutyric aciduria.
Packaging:	Bottomless glass bottle. Contents are inside inserted fused cone.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥96.0% (GC); ≥96.0%
Storage Temp.	2-8°C
UNSPSC	12352106