Synonym: Axerophthol; Vitamin A; Vitamin A alcohol; Vitamin A1; all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
CAS Number: 68-26-8
Empirical Formula (Hill Notation): C20H30O
Molecular Weight: 286.45
EC Number: 200-683-7
MDL Number: MFCD00001552
Linear Formula: C20H30O
Product Type: Chemical
| assay |
≥95.0% (HPLC) |
| biological source |
synthetic |
| color |
yellow to dark yellow |
| form |
(Powder or Crystal with Lumps) |
| InChI |
1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+ |
| InChI key |
FPIPGXGPPPQFEQ-OVSJKPMPSA-N |
| mp |
61-63 °C (lit.) |
| Quality Level |
100  |
| shipped in |
dry ice |
| SMILES string |
CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1 |
| specific activity |
~2700 U/mg |
| storage temp. |
−20°C |
| Application: |
Retinol has been used as a standard in ultra-performance liquid chromatography - tandem mass spectrometer (UPLC-MS/MS) for the vitamins detection and quantification. |
| Biochem/physiol Actions: |
Retinol and its derivatives exhibit anti-aging properties. Retinol is used for treating wrinkles and signs of aging. However, due to its photo instability and skin irritation potency, it is hardly used in cosmetic formulations. Retinol is also used as a therapeutic for dermatoses. Its deficiency leads to xerosis and follicular hyperkeratosis. |
| General description: |
Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinol is biologically active in a wide range of processes. |
| General description: |
Retinol or all-trans-retinol is a 20-carbon molecule with cyclohexenyl ring, a side chain with four double bonds (all in trans configuration) and an alcohol end group. |
| Unit Definition: |
1 U corresponds to 1 international U acc. to Ph Eur II, 217 (1983) |
| Purity |
≥95.0% (HPLC) |
| activity |
specific activity: ~2700 U/mg |
| mp |
61-63 °C (lit.) |
| Storage Temp. |
−20°C |
| UNSPSC |
12352205 |
