Byzen Pro™ Protein A resin
SIGMA/18887 - suitable for affinity chromatography
Product Type: Chemical
| form | suspension |
| mean particle size | 70 μm |
| Quality Level | 100  |
| storage temp. | 2-8°C |
| technique(s) | affinity chromatography: suitable |
| Application: | Byzen Pro™ Protein A resin is an affinity chromatography medium in which a novel Protein A mutant is used as a ligand. Conventional protein A resins use strongly acidic buffers to elute antibodies, exposing the target antibody to the risks of aggregation and decreased activities. In contrast, this temperature- responding Byzen Pro™ Protein A resin allows antibodies to be eluted under neutral pH by a simple temperature change. This eliminates any risk of aggregation and decreased activity of the antibody, improving manufacturing efficiency for pharmaceutical antibodies. |
| Features and Benefits: | Typical Product Profile: Bead Structure, Cross-linked polyvinyl alcohol, Mean Particle Size 70 μm, Max. Back Pressure 0.3 MPa, Flow Rate (Recommended) 125-250 cm/h, pH Range (Recommended) pH 6-8, Ligand: Recombinant Protein A mutant, Ligand Immobilization: Multiple ligation, Dynamic Binding Capacity (20 cm column): 26 g/L (250 cm/h) 34 g/L (125 cm/h), Total Binding Capacity 40 g/L, Binding Temperature Below 10°C, Eluting Temperature 37 to 40°C, Mode of Temperature Change: Conventional heat exchange system can be used. |
| Legal Information: | Byzen Pro is a trademark of Nomadic Bioscience Co., Ltd |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 13111000 |