Byzen Pro^™ Protein A resin

SIGMA/18887 - suitable for affinity chromatography

Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-18887-1ML	1 mL	$331.00 1/EAAdd To Favorites		Add To Favorites
45-18887-5ML	5 mL	$1290.00 1/EAAdd To Favorites		Add To Favorites

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form	suspension
mean particle size	70 μm
Quality Level	100
storage temp.	2-8°C
technique(s)	affinity chromatography: suitable

Application:	Byzen Pro^™ Protein A resin is an affinity chromatography medium in which a novel Protein A mutant is used as a ligand. Conventional protein A resins use strongly acidic buffers to elute antibodies, exposing the target antibody to the risks of aggregation and decreased activities. In contrast, this temperature- responding Byzen Pro^™ Protein A resin allows antibodies to be eluted under neutral pH by a simple temperature change. This eliminates any risk of aggregation and decreased activity of the antibody, improving manufacturing efficiency for pharmaceutical antibodies.
Features and Benefits:	Typical Product Profile: Bead Structure, Cross-linked polyvinyl alcohol, Mean Particle Size 70 μm, Max. Back Pressure 0.3 MPa, Flow Rate (Recommended) 125-250 cm/h, pH Range (Recommended) pH 6-8, Ligand: Recombinant Protein A mutant, Ligand Immobilization: Multiple ligation, Dynamic Binding Capacity (20 cm column): 26 g/L (250 cm/h) 34 g/L (125 cm/h), Total Binding Capacity 40 g/L, Binding Temperature Below 10°C, Eluting Temperature 37 to 40°C, Mode of Temperature Change: Conventional heat exchange system can be used.
Legal Information:	Byzen Pro is a trademark of Nomadic Bioscience Co., Ltd