Alpha-Fetoprotein Rabbit Polyclonal Antibody
SIGMA/203A-1
Product Type: Chemical
Immunohistochemistry Alpha-Fetoprotein (polyclonal) on fetal liver
| antibody form | Ig fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| control | fetal liver |
| description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| form | buffered aqueous solution |
| manufacturer/tradename | Cell Marque™ |
| packaging | bottle of 1.0 mL predilute (203A-17) |
| bottle of 7.0 mL predilute (203A-18) | |
| vial of 0.1 mL concentrate (203A-14) | |
| vial of 0.5 mL concentrate (203A-15) | |
| vial of 1.0 mL concentrate (203A-16) | |
| Quality Level | 100  |
| 500 |
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| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 |
| visualization | cytoplasmic |
| General description: | Alpha-fetoprotein (AFP) is a fetal tumor-associated polypeptide of the albuminoid gene family that binds and transports molecules in addition to many other proposed functions. This secretory protein is produced by the fetal yolk sac and liver but is found only in trace amounts in adult liver. AFP expression by immunohistochemistry is seen in hepatocellular carcinoma (HCC). Positive staining with anti-AFP is seen in hepatocytes of the fetal liver and hepatoma. Since only traces of AFP are found in adult serum, elevated levels suggest either a benign or malignant lesion of the liver, a yolk sac carcinoma, or one of a few other tumors. Correspondingly, in conjunction with elevated serum levels, AFP has been immunohistochemically demonstrated in yolk sac tumors of gonadal and extragonadal sites, in hepatic malignancies, and in a few other neoplasms. The antigen is not denatured by most fixatives. |
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| Legal Information: | Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany | ||||
| Linkage: | Alpha-Fetoprotein Positive Control Slides, Product No. 203S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). |
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| Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
| Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide | ||||
| Preparation Note: | Download the IFU specific to your product lot and format  Note: This requires a keycode which can be found on your packaging or product label. |
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| Quality: |
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| RIDADR | NONH for all modes of transport |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |