Alpha-Fetoprotein Rabbit Polyclonal Antibody

SIGMA/203A-1

Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-203A-14	0.1 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-203A-15	0.5 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-203A-16	1 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-203A-16-RUO	1 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-203A-17	1 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-203A-18	7 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites

Immunohistochemistry Alpha-Fetoprotein (polyclonal) on fetal liver

antibody form	Ig fraction of antiserum
antibody product type	primary antibodies
biological source	rabbit
clone	polyclonal
conjugate	unconjugated
control	fetal liver
description	For In Vitro Diagnostic Use in Select Regions (See Chart)
form	buffered aqueous solution
manufacturer/tradename	Cell Marque^™
packaging	bottle of 1.0 mL predilute (203A-17)
	bottle of 7.0 mL predilute (203A-18)
	vial of 0.1 mL concentrate (203A-14)
	vial of 0.5 mL concentrate (203A-15)
	vial of 1.0 mL concentrate (203A-16)
Quality Level	100
	500
shipped in	wet ice
species reactivity	human
storage temp.	2-8°C
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
visualization	cytoplasmic

General description:

Alpha-fetoprotein (AFP) is a fetal tumor-associated polypeptide of the albuminoid gene family that binds and transports molecules in addition to many other proposed functions. This secretory protein is produced by the fetal yolk sac and liver but is found only in trace amounts in adult liver. AFP expression by immunohistochemistry is seen in hepatocellular carcinoma (HCC).
Positive staining with anti-AFP is seen in hepatocytes of the fetal liver and hepatoma. Since only traces of AFP are found in adult serum, elevated levels suggest either a benign or malignant lesion of the liver, a yolk sac carcinoma, or one of a few other tumors. Correspondingly, in conjunction with elevated serum levels, AFP has been immunohistochemically demonstrated in yolk sac tumors of gonadal and extragonadal sites, in hepatic malignancies, and in a few other neoplasms. The antigen is not denatured by most fixatives.

Legal Information:

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Linkage:

Alpha-Fetoprotein Positive Control Slides, Product No. 203S External link

, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes:

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form:

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note:

Download the IFU specific to your product lot and format External link

Note: This requires a keycode which can be found on your packaging or product label.

Quality:

IVD

RUO

Storage Temp.	2-8°C
UNSPSC	12352203