5(6)-Carboxy-2′,7′-dichlorofluorescein

SIGMA/21882 - BioReagent, suitable for fluorescence, ≥95% (TLC)

CAS Number: 111843-78-8
Empirical Formula (Hill Notation): C₂₁H₁₀Cl₂O₇
Molecular Weight: 445.21
MDL Number: MFCD00037452
Linear Formula: C₂₁H₁₀Cl₂O₇
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-21882-100MG-F	100 mg	$191.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (TLC)
fluorescence	λ_ex 504 nm; λ_em 529 nm in 0.1 M Tris pH 8.0
form	solid
InChI	1S/2C21H10Cl2O7/c22-13-4-11-17(6-15(13)24)30-18-7-16(25)14(23)5-12(18)19(11)10-3-8(20(26)27)1-2-9(10)21(28)29;22-13-4-11-17(6-15(13)24)30-18-7-16(25)14(23)5-12(18)19(11)9-2-1-8(20(26)27)3-10(9)21(28)29/h2*1-7,24H,(H,26,27)(H,28,29)
InChI key	WHFHRELKGQJJBQ-UHFFFAOYSA-N
mp	≥250 °C (lit.)
pKa	5.1
product line	BioReagent
Quality Level	100
SMILES string	OC(=O)c1ccc(c(c1)C(O)=O)C2=C3C=C(Cl)C(=O)C=C3Oc4cc(O)c(Cl)cc24.OC(=O)c5ccc(C(O)=O)c(c5)C6=C7C=C(Cl)C(=O)C=C7Oc8cc(O)c(Cl)cc68
solubility	DMF: soluble
	DMSO: soluble
	H₂O: soluble (pH ≥ 5)
suitability	suitable for fluorescence

Application:	5(6)-Carboxy-2′,7′-dichlorofluorescein may be used as a specific substrate/probe to study the identity, activity and specificity of multidrug resistance protein 2 (MRP2) molecules.
Application:	suitable as pH-indicator
Other Notes:	Fluorescent intracellular pH indicator in the pH 4-5 range

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (TLC)
mp	≥250 °C (lit.)
UNSPSC	12352200

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