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Quinine hemisulfate salt monohydrate

SIGMA/22640 - BioReagent, suitable for fluorescence, 99.0-101.0%

Synonym: Quinine sulfate (2:1) (salt) dihydrate

CAS Number: 207671-44-1
Empirical Formula (Hill Notation): C20H24N2O2 · 0.5H2O4S · H2O
Molecular Weight: 391.47
MDL Number: MFCD00150790
Linear Formula: C20H24N2O2 · 0.5H2O4S · H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-22640-5G 5 g
 $60.30
1/EA		 Add To Favorites
45-22640-25G 25 g
 $233.00
1/EA		 Add To Favorites

 

antibiotic activity spectrum parasites
assay 99.0-101.0%
fluorescence λex 347 nm; λem 448 nm in 0.5 M sulfuric acid
InChI 1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1
InChI key ZHNFLHYOFXQIOW-LPYZJUEESA-N
mode of action enzyme | inhibits
mp ~225 °C (dec.) (lit.)
product line BioReagent
Quality Level 200 
SMILES string O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5
suitability suitable for fluorescence
Application: Quinine hemisulfate salt monohydrate is used for indirect photometric detection of polyamines in biological samples. It is suitable for studying metabolism of bio crystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
Biochem/physiol Actions: Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
General description: Quinine hemisulfate salt monohydrate is a naturally occurring well known fluorescent standard material. Quinine hemisulfate salt monohydrate or QSM has a fluorescence lifetime between 1.0 to 3.0 ns.
Purity 99.0-101.0%
mp ~225 °C (dec.) (lit.)
UNSPSC 12352210

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