BCL6 (EP278) Rabbit Monoclonal Primary Antibody
SIGMA/227R-2
Product Type: Chemical
Immunohistochemistry BCL6 (EP278) on lymph node.
Immunohistochemistry BCL6 antibody shows nuclear positivity in the neoplastic cells of nodular lymphocyte predominant Hodgkin lymphoma.
Immunohistochemistry BCL6 (EP278) on tonsil, germinal center
| antibody form | culture supernatant |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | EP278, monoclonal |
| conjugate | unconjugated |
| control | tonsil |
| description | (For In Vitro Diagnostic Use in Select Regions (See Chart)) |
| form | buffered aqueous solution |
| isotype | IgG |
| manufacturer/tradename | Cell Marque™ |
| packaging | bottle of 1.0 mL predilute (227R-27) |
| bottle of 7.0 mL predilute (227R-28) | |
| vial of 0.1 mL concentrate (227R-24) | |
| vial of 0.1 mL concentrate Research Use Only (227R-24-RUO) | |
| vial of 0.5 mL concentrate (227R-25) | |
| vial of 1.0 mL concentrate (227R-26) | |
| vial of 1.0 mL concentrate Research Use Only (227R-26-RUO) | |
| vial of 1.0 mL pre-dilute Research Use Only (227R-27-RUO) | |
| vial of 7.0 mL pre-dilute ready-to-use Research Use Only (227R-28-RUO) | |
| Quality Level | 100  |
| 500 |
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| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
| visualization | nuclear |
| General description: | BCL6 is a transcriptional regulator gene which codes for a 706-amino-acid nuclear zinc finger protein.1 In normal tissue these antibodies have strong nuclear staining for a subset of B-lymphocytes, mostly located in germinal centers (GC).2 BCL6 antibodies stain malignant cells in follicular lymphoma,3 diffuse large B-cell lymphomas,4 Burkitt lymphoma,4 classical Hodgkin lymphoma,5 as well as majority of tumor cells in nodular lymphocyte predominant Hodgkin lymphoma.6 BCL6 expression has been also seen in anaplastic large cell lymphomas (ALCL).7 | ||||
| Legal Information: | Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany | ||||
| Linkage: | BCL6 Positive Control Slides, Product No. 227S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). |
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| Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
| Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide. | ||||
| Preparation Note: | Download the IFU specific to your product lot and format  Note: This requires a keycode which can be found on your packaging or product label. |
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| Quality: |
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| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |