1,8-Dihydroxy-3-methylanthraquinone

SIGMA/229075 - 98%

Synonym: 3-Methylchrysazin; Chrysophanic acid

CAS Number: 481-74-3
Empirical Formula (Hill Notation): C₁₅H₁₀O₄
Molecular Weight: 254.24
EC Number: 207-572-2
MDL Number: MFCD00001208
Linear Formula: C₁₅H₁₀O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-229075-50MG	50 mg	$94.60 1/EAAdd To Favorites		Add To Favorites
45-229075-1G	1 g	$768.00 1/EAAdd To Favorites		Add To Favorites

antibiotic activity spectrum	neoplastics
	viruses
assay	98%
color	yellow-orange
form	crystalline
InChI	1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
InChI key	LQGUBLBATBMXHT-UHFFFAOYSA-N
mode of action	enzyme \| inhibits
Quality Level	100
SMILES string	Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
solubility	chloroform: 1%

Application:	Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells . It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro .
Biochem/physiol Actions:	Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway . Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus .
Other Notes:	Keep container tightly closed in a dry and well-ventilated place.
Packaging:	1 g in glass bottle
Packaging:	50 mg in glass insert

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable