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1,8-Dihydroxy-3-methylanthraquinone

SIGMA/229075 - 98%

Synonym: 3-Methylchrysazin; Chrysophanic acid

CAS Number: 481-74-3
Empirical Formula (Hill Notation): C15H10O4
Molecular Weight: 254.24
EC Number: 207-572-2
MDL Number: MFCD00001208
Linear Formula: C15H10O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-229075-50MG 50 mg
 $124.00
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45-229075-1G 1 g
 $997.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 229075-50MG.

 

antibiotic activity spectrum neoplastics
  viruses
assay 98%
color yellow-orange
form crystalline
InChI 1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
InChI key LQGUBLBATBMXHT-UHFFFAOYSA-N
mode of action enzyme | inhibits
Quality Level 100 
SMILES string Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
solubility chloroform: 1%
Application: Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells . It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro .
Biochem/physiol Actions: Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway . Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus .
Other Notes: Keep container tightly closed in a dry and well-ventilated place.
Packaging: 1 g in glass bottle
Packaging: 50 mg in glass insert
Purity 98%
UNSPSC 51102829

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