2-Bromohexadecanoic acid

SIGMA/238422 - ~97%

Synonym: 2-Bromopalmitic acid

CAS Number: 18263-25-7
Empirical Formula (Hill Notation): C₁₆H₃₁BrO₂
Molecular Weight: 335.32
EC Number: 242-137-0
MDL Number: MFCD00004215
Linear Formula: CH₃(CH₂)₁₃CH(Br)CO₂H
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-238422-10G	10 g	$52.80 1/EAAdd To Favorites		Add To Favorites
45-238422-50G	50 g	$203.00 1/EAAdd To Favorites		Add To Favorites

assay	~97%
form	solid
InChI	1S/C16H31BrO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(17)16(18)19/h15H,2-14H2,1H3,(H,18,19)
InChI key	DPRAYRYQQAXQPE-UHFFFAOYSA-N
Quality Level	100
SMILES string	CCCCCCCCCCCCCCC(Br)C(O)=O

Biochem/physiol Actions:	2-Bromohexadecanoic acid is a PPARδ agonist. It has also been shown to inhibit fatty acid oxidation, inhibit DHHC-mediated palmitoylation, and promote glucose uptake in rat cardiac cells and the insulin-sensitive murine fibroblast line A31-IS.
General description:	PPARδ (peroxisome proliferator-activated receptor, delta isoform) acts as a transcription factor for gene expression as well as playing a role in lipid metabolism regulation; activity of this receptor is ligand-regulated. 2-Bromohexadecanoic acid is a metabolically stable analoge of the fatty acid palmitic acid that has been shown to be a natural ligand for the PPARδ receptor. 2-Bromohexadecanoic acid has also been used in studies of fatty acid oxidation, palmitoylation, and glucose uptake.
Packaging:	10, 50 g in poly bottle