2-Bromohexadecanoic acid
SIGMA/238422 - ~97%
Synonym: 2-Bromopalmitic acid
CAS Number: 18263-25-7
Empirical Formula (Hill Notation): C16H31BrO2
Molecular Weight: 335.32
EC Number: 242-137-0
MDL Number: MFCD00004215
Linear Formula: CH3(CH2)13CH(Br)CO2H
Product Type: Chemical
assay | ~97% |
form | solid |
InChI | 1S/C16H31BrO2/c1-2-3-4-5- |
InChI key | DPRAYRYQQAXQPE-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | CCCCCCCCCCCCCCC(Br)C(O)=O |
Biochem/physiol Actions: | 2-Bromohexadecanoic acid is a PPARδ agonist. It has also been shown to inhibit fatty acid oxidation, inhibit DHHC-mediated palmitoylation, and promote glucose uptake in rat cardiac cells and the insulin-sensitive murine fibroblast line A31-IS. |
General description: | PPARδ (peroxisome proliferator-activated receptor, delta isoform) acts as a transcription factor for gene expression as well as playing a role in lipid metabolism regulation; activity of this receptor is ligand-regulated. 2-Bromohexadecanoic acid is a metabolically stable analoge of the fatty acid palmitic acid that has been shown to be a natural ligand for the PPARδ receptor. 2-Bromohexadecanoic acid has also been used in studies of fatty acid oxidation, palmitoylation, and glucose uptake. |
Packaging: | 10, 50 g in poly bottle |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | 235.4 °F - closed cup |
Flash Point(C) | 113 °C - closed cup |
Purity | ~97% |
UNSPSC | 12352203 |