Glucagon (EP74) Rabbit Monoclonal Primary Antibody

SIGMA/259R-1

Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-259R-14	0.1 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-259R-15	0.5 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-259R-16	1 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-259R-17	1 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-259R-18	7 mL	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites

Immunohistochemistry Glucagon (EP74) on pancreatic neuroendocrine tumor.

antibody form	culture supernatant
antibody product type	primary antibodies
biological source	rabbit
clone	EP74, monoclonal
conjugate	unconjugated
description	(For In Vitro Diagnostic Use in Select Regions (See Chart))
form	buffered aqueous solution
isotype	IgG
manufacturer/tradename	Cell Marque^™
packaging	bottle of 1.0 mL predilute (259R-17)
	bottle of 7.0 mL predilute (259R-18)
	vial of 0.1 mL concentrate (259R-14)
	vial of 0.5 mL concentrate (259R-15)
	vial of 1.0 mL concentrate (259R-16)
Quality Level	100
	500
shipped in	wet ice
species reactivity	human
storage temp.	2-8°C
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200

General description:

The normal islets of Langerhans (pancreas) contain four major cell types, 15-20% of which are alpha cells which produce glucagon.¹ Alpha cell tumors can be divided into two distinct types; those associated with glucagonoma syndrome² (necrolytic migratory erythema, diabetes, anemia, stomatitis, weight loss, venous thromboses, diarrhea, and sometimes psychiatric disturbances), and those which are not. Those associated with the syndrome tend to be large and solitary and there is a high incidence of malignancy. Those glucagonomas not associated with the syndrome tend to be multiple and small and are nearly always benign.³Immunohistochemically, the two types of glucagonomas are reactive to the glucagon antibody, though occasionally only weakly.

Legal Information:

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Linkage:

Glucagon Positive Control Slides, Product No. 259S External link

, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes:

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form:

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note:

Download the IFU specific to your product lot and format External link

Note: This requires a keycode which can be found on your packaging or product label.

Quality:

IVD

RUO

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-8°C
UNSPSC	12352203