Chlortetracycline hydrochloride

SIGMA/26430 - BioReagent, suitable for fluorescence, from Streptomyces aureofaciens, ≥85.0% (HPLC)

Synonym: 7-Chlorotetracycline hydrochloride

CAS Number: 64-72-2
Empirical Formula (Hill Notation): C₂₂H₂₃ClN₂O₈ · HCl
Molecular Weight: 515.34
EC Number: 200-591-7
MDL Number: MFCD00082440
Linear Formula: C₂₂H₂₃ClN₂O₈ · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-26430-5G	5 g	$70.50 1/EA		Add To Favorites
45-26430-100G	100 g	$495.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-negative bacteria
	Gram-positive bacteria
assay	≥85.0% (HPLC)
biological source	Streptomyces aureofaciens
color	faintly yellow to yellow
form	powder or crystals
InChI	1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1
InChI key	CBHYYLPALVVVEY-LYNLVHCPSA-N
mode of action	protein synthesis \| interferes
mp	210-215 °C (dec.) (lit.)
product line	BioReagent
Quality Level	200
SMILES string	Cl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O
solubility	H₂O: 50 mg/mL
storage temp.	−20°C
suitability	suitable for fluorescence

Application:	Cell-permeable fluorescent probe for Ca²⁺ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.
Biochem/physiol Actions:	Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens. Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-positive. Less active against Gram-negative bacteria than tetracycline. Mode of Resistance: Loss of cell wall permeability.
General description:	Chemical structure: tetracycline
Other Notes:	Keep container tightly closed in a dry and well-ventilated place.
Packaging:	5 g, 25 g, 100g
Quality:	Recommended for fluorescent studies of calcium signaling in cells or tissues.

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥85.0% (HPLC)
mp	210-215 °C (dec.) (lit.)
Storage Temp.	−20°C
UNSPSC	51101500

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