INI-1 (MRQ-27) Mouse Monoclonal Antibody
SIGMA/272M-1
Product Type: Chemical
Immunohistochemistry INI-1 (MRQ-27) on brain tissue
| antibody form | culture supernatant |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | MRQ-27, monoclonal |
| conjugate | unconjugated |
| control | brain, endothelial cells |
| description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| form | buffered aqueous solution |
| manufacturer/tradename | Cell Marque® |
| packaging | bottle of 1.0 mL predilute (272M-17) |
| bottle of 7.0 mL predilute (272M-18) | |
| vial of 0.1 mL concentrate (272M-14) | |
| vial of 0.5 mL concentrate (272M-15) | |
| vial of 1.0 mL concentrate (272M-16) | |
| Quality Level | 100  |
| 500 |
|
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
| visualization | nuclear |
| Analysis Note: |
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| General description: | INI-1, also known as SMARCB1, is one of the core subunit proteins of the ATP-dependent SWI/SNF chromatin remodeling complex. It is involved in chromatin remodeling and transcriptional regulation and functions as a tumor suppressor. Nuclear INI-1 expression is seen in virtually all normal human tissues and most malignancies but the INI-1 gene is often mutated or deleted in malignant rhabdoid tumors (MRT), including those arising in the central nervous system, leading to a lack of INI-1 expression. | ||||
| Legal Information: | Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany | ||||
| Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
| Other Notes: | INI-1 Positive Control Slides, Product No. 272S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). |
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| Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide | ||||
| Preparation Note: | Download the IFU specific to your product lot and format  Note: This requires a keycode which can be found on your packaging or product label. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |