INI-1 (MRQ-27) Mouse Monoclonal Antibody
SIGMA/272M-1
Product Type: Chemical
antibody form | culture supernatant |
antibody product type | primary antibodies |
biological source | mouse |
clone | MRQ-27, monoclonal |
conjugate | unconjugated |
control | brain, endothelial cells |
description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
form | buffered aqueous solution |
manufacturer/tradename | Cell Marque™ |
packaging | bottle of 1.0 mL predilute (272M-17) |
bottle of 7.0 mL predilute (272M-18) | |
vial of 0.1 mL concentrate (272M-14) | |
vial of 0.5 mL concentrate (272M-15) | |
vial of 1.0 mL concentrate (272M-16) | |
Quality Level | 100 ![]() |
500 ![]() |
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shipped in | wet ice |
species reactivity | human |
storage temp. | 2-8°C |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
visualization | nuclear |
General description: | INI-1, also known as SMARCB1, is one of the core subunit proteins of the ATP-dependent SWI/SNF chromatin remodeling complex. It is involved in chromatin remodeling and transcriptional regulation and functions as a tumor suppressor. Nuclear INI-1 expression is seen in virtually all normal human tissues and most malignancies but the INI-1 gene is often mutated or deleted in malignant rhabdoid tumors (MRT), including those arising in the central nervous system, leading to a lack of INI-1 expression. | ||||
Legal Information: | Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany | ||||
Linkage: | INI-1 Positive Control Slides, Product No. 272S ![]() |
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Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide | ||||
Preparation Note: | Download the IFU specific to your product lot and format ![]() ![]() |
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Quality: |
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RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 12352203 |