Kappa (L1C1) Mouse Monoclonal Antibody
SIGMA/274M-9
Product Type: Chemical
antibody form | culture supernatant |
antibody product type | primary antibodies |
biological source | mouse |
clone | L1C1, monoclonal |
conjugate | unconjugated |
control | tonsil |
description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
form | buffered aqueous solution |
isotype | IgG1κ |
manufacturer/tradename | Cell Marque™ |
packaging | bottle of 1.0 mL predilute (274M-97) |
bottle of 7.0 mL predilute (274M-98) | |
vial of 0.1 mL concentrate (274M-94) | |
vial of 0.5 mL concentrate (274M-95) | |
vial of 1.0 mL concentrate (274M-96) | |
Quality Level | 100 ![]() |
500 ![]() |
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shipped in | wet ice |
species reactivity | human |
storage temp. | 2-8°C |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
visualization | cytoplasmic |
General description: | Anti-Kappa detects surface immunoglobulin on normal and neoplastic B-cells. In paraffin-embedded tissue, anti-kappa exhibits strong staining of kappa-positive plasma cells and cells that have absorbed exogenous immunoglobulins. When dealing with B-cell neoplasms, the determination of light chain ratios remains the centerpiece. Most B-cell lymphomas express either kappa or lambda light chains, whereas reactive proliferations display a mixture of kappa and lambda positive cells. If only a single light chain type is detected, a lymphoproliferative disorder exists. Monoclonality is determined by a kappa-lambda ratio of greater than or equal to 3:1 or a lambda-kappa ratio greater than 2:1. | ||||
Legal Information: | Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany | ||||
Linkage: | Kappa Positive Control Slides, Product No. 274S ![]() |
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Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide | ||||
Preparation Note: | Download the IFU specific to your product lot and format ![]() ![]() |
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Quality: |
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RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 12352203 |