Cloxacillin sodium salt
SIGMA/27555 - ≥95.0% (HPLC)
Synonym: 3-
CAS Number: 642-78-4
Empirical Formula (Hill Notation): C19H17ClN3NaO5S
Molecular Weight: 457.86
EC Number: 211-390-9
MDL Number: MFCD00063568
Linear Formula: C19H17ClN3NaO5S
Product Type: Chemical
antibiotic activity spectrum | Gram-positive bacteria |
assay | ≥95.0% (HPLC) |
biological source | semisynthetic |
color | white to off-white |
form | powder or crystals |
impurities | ≤5% Total impurities (anhydrous) |
InChI | 1S/C19H18ClN3O5S.Na/c1-8- |
InChI key | SCLZRKVZRBKZCR-SLINCCQESA |
mode of action | cell wall synthesis | interferes |
Quality Level | 200 |
SMILES string | [Na+].Cc1onc(-c2ccccc2Cl) |
storage temp. | 2-8°C |
Application: | Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is used against staphylococci that produce β-lactamase. It is used to study the role of pH in antibiotic effectiveness and how oxgall, acid, and hydrogen peroxide stress effects the susceptibility of Bifidobacteria. |
Biochem/physiol Actions: | Cloxacillin interferes with the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins. This inhibits the necessary cross-linking and leads to autolysis of the bacteria by autolysins. |
General description: | Chemical structure: ß-lactam |
Other Notes: | Keep container tightly closed in a dry and well-ventilated place. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95.0% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 51101500 |