Galangin

SIGMA/282200 - autophagy inducing flavonoid

Synonym: 3,5,7-Trihydroxyflavone; Norizalpinin

CAS Number: 548-83-4
Empirical Formula (Hill Notation): C₁₅H₁₀O₅
Molecular Weight: 270.24
EC Number: 208-960-4
MDL Number: MFCD00006833
Linear Formula: C₁₅H₁₀O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-282200-25MG	25 mg	$0.00 1/EA CALL FOR PRICEAdd To Favorites		Add To Favorites
45-282200-100MG	100 mg	$595.00 1/EAAdd To Favorites		Add To Favorites

assay	≥95% (HPLC)
color	yellow
form	powder
InChI	1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H
InChI key	VCCRNZQBSJXYJD-UHFFFAOYSA-N
mp	214-215 °C (lit.)
Quality Level	100
SMILES string	Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3ccccc3

Application:	Galangin has been used: • as a test drug to test its ameliorative effect in a rodent model of cisplatin-induced nephrotoxicity • to test its effect on the differentiation of 3T3-L1 preadipocyte cells into adipocytes • as an internal standard in nuclear magnetic resonance spectroscopy and mass spectroscopy
Biochem/physiol Actions:	Galangin exhibits antioxidant, anti-apoptotic, anti-inflammatory and anti-obesity properties. In addition, it also possesses anti-genotoxic activity against environmental and dietary carcinogens. Galangin inhibits cancer growth by hindering cancer cell proliferation, induction of apoptosis and autophagy and inhibition of metastasis. Galangin also has an ability to inhibit CYP1A1 (Cytochrome P450, family 1, member A1) activity.
General description:	Galangin is a flavonoid isolated from members of the Zingiberaceae family, which are mainly used for herbal medicines.
Packaging:	25, 100 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P301 + P312 + P330
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable