Galangin
SIGMA/282200 - autophagy inducing flavonoid
Synonym: 3,5,7-
CAS Number: 548-83-4
Empirical Formula (Hill Notation): C15H10O5
Molecular Weight: 270.24
EC Number: 208-960-4
MDL Number: MFCD00006833
Linear Formula: C15H10O5
Product Type: Chemical
| assay | ≥95% (HPLC) |
| color | yellow |
| form | powder |
| InChI | 1S/C15H10O5/c16-9-6-10(17 |
| InChI key | VCCRNZQBSJXYJD-UHFFFAOYSA |
| mp | 214-215 °C (lit.) |
| Quality Level | 100  |
| SMILES string | Oc1cc(O)c2C(=O)C(O)=C(Oc2 |
| Application: | Galangin has been used: • as a test drug to test its ameliorative effect in a rodent model of cisplatin-induced nephrotoxicity • to test its effect on the differentiation of 3T3-L1 preadipocyte cells into adipocytes • as an internal standard in nuclear magnetic resonance spectroscopy and mass spectroscopy |
| Biochem/physiol Actions: | Galangin exhibits antioxidant, anti-apoptotic, anti-inflammatory and anti-obesity properties. In addition, it also possesses anti-genotoxic activity against environmental and dietary carcinogens. Galangin inhibits cancer growth by hindering cancer cell proliferation, induction of apoptosis and autophagy and inhibition of metastasis. Galangin also has an ability to inhibit CYP1A1 (Cytochrome P450, family 1, member A1) activity. |
| General description: | Galangin is a flavonoid isolated from members of the Zingiberaceae family, which are mainly used for herbal medicines. |
| Packaging: | 25, 100 mg in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301 + P312 + P330 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| mp | 214-215 °C (lit.) |
| UNSPSC | 12352200 |