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CHES

SIGMA/29311 - BioUltra, ≥99.5% (T)

Synonym: 2-(Cyclohexylamino)ethanesulfonic acid

CAS Number: 103-47-9
Empirical Formula (Hill Notation): C8H17NO3S
Molecular Weight: 207.29
EC Number: 203-115-6
MDL Number: MFCD00003835
Linear Formula: C8H17NO3S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-29311-10G 10 g
$83.20
1/EA
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45-29311-50G 50 g
$268.00
1/EA
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λ 0.5 M in H2O
anion traces chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤500 mg/kg
assay ≥99.5% (T)
cation traces Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
form powder
ign. residue ≤0.05%
impurities insoluble matter, passes filter test
InChI 1S/C8H17NO3S/c10-13(11,12)7-6-9-8-4-2-1-3-5-8/h8-9H,1-7H2,(H,10,11,12)
InChI key MKWKNSIESPFAQN-UHFFFAOYSA-N
loss ≤0.5% loss on drying, 110 °C
pH 3.0-5.0 (25 °C, 0.5 M in H2O)
pKa (25 °C) 9.3
product line BioUltra
Quality Level 200 
SMILES string OS(=O)(=O)CCNC1CCCCC1
solubility H2O: 0.5 M at 20 °C, clear, colorless
useful pH range 8.6-10.0
UV absorption λ: 260 nm Amax: 0.08
  λ: 280 nm Amax: 0.05
Application: 2-(Cyclohexylamino)ethanesulfonic acid (CHES) has been used in the preparation of dimethyl trisulfide- polysorbate 80 (DMTS-PS80) formulation.
General description: Cyclohexylaminoethanesulfonic acid (CHES) is a buffering agent. Its structure contains a hydrophilic taurine (2-aminoethanesulfonic acid) moiety and a hydrophobic cyclohexyl group. CHES binds to the active site of several enzymes and inhibits substrate binding and enzymatic activity. Therefore, CHES may be used as a scaffold for new drug development for regulating enzyme activity.
Other Notes: Buffer for studying pH-dependent processes in enzymology; Has a high affinity for the iodoacetate binding site of liver alcohol dehydrogenase.
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99.5% (T)
UNSPSC 12161700

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