D-Cycloserine

SIGMA/30020

Synonym: R-4-Amino-3-isoxazolidinone; (R)-4-Amino-3-isoxazolidone; 4-Amino-3-isoxazolidinone

CAS Number: 68-41-7
Empirical Formula (Hill Notation): C₃H₆N₂O₂
Molecular Weight: 102.09
EC Number: 200-688-4
MDL Number: MFCD00005353
Linear Formula: C₃H₆N₂O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-30020-1G	1 g	$91.40 1/EA	Add To Favorites
45-30020-5G	5 g	$418.00 1/EA	Add To Favorites
45-30020-25G	25 g	$1470.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-negative bacteria
	Gram-positive bacteria
	mycobacteria
biological source	synthetic
color	white to off-white
form	powder
InChI	1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
InChI key	DYDCUQKUCUHJBH-UWTATZPHSA-N
mode of action	cell wall synthesis \| interferes
mp	147 °C (dec.) (lit.)
potency	≥900 μg per mg
Quality Level	100
SMILES string	N[C@@H]1CONC1=O
storage temp.	−20°C

Application:	D-Cycloserine acts as inhibitor of various enzymes.
Biochem/physiol Actions:	Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic. Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors; antibiotic against Gram-negative bacteria. Mode of Resistance: D-Ala transport interference.
Biochem/physiol Actions:	Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic. Mode of Resistance: D-Ala transport interference.
General description:	Chemical structure: amino acid derivatives
Other Notes:	Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Air sensitive. Keep in a dry place.
Packaging:	1g, 5g, 25g

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	147 °C (dec.) (lit.)
Storage Temp.	−20°C
UNSPSC	51101500

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