Cysteamine
SIGMA/30070 - ≥98.0% (RT)
Synonym: β-Mercaptoethylamine; 2-Aminoethanethiol; 2-Mercaptoethylamine; Decarboxycysteine; MEA; Thioethanolamine
CAS Number: 60-23-1
Empirical Formula (Hill Notation): C2H7NS
Molecular Weight: 77.15
EC Number: 200-463-0
MDL Number: MFCD00008196
Linear Formula: NH2CH2CH2SH
Product Type: Chemical
assay | ≥98.0% (RT) |
InChI | 1S/C2H7NS/c3-1-2-4/h4H,1- |
InChI key | UFULAYFCSOUIOV-UHFFFAOYSA |
Quality Level | 200 |
SMILES string | NCCS |
storage temp. | 2-8°C |
Application: | Cysteamine is suitable for use: • in the preparation of cysteamine modified gold nanoparticles (AuNP) • in the fabrication of SU-8 microrods, where in, the amine group of cysteamine reacts with the unreacted epoxide rings present on the surface of the particles, thereby opening it and forming a covalent bond • to enhance in vitro development of porcine oocytes matured and fertilized in vitro • in a study to demonstrate the depletion effect of cysteamine on cystinotic leucocyte granular fractions of cystine by disulphide interchange • as a radioprotector • to administer subcutaneously in rats to study its blocking effect on somatostatin secretion without modifying the pancreatic insulin or glucagon content • as a scavenger in electrophoretic gels (acetic acid/urea gels) |
Biochem/physiol Actions: | Cysteamine (β-mercaptoethylamine) depletes cystine from patient′s cells and there by regulates renal glomerular function and increases growth in them. Therefore, cysteamine is considered to be a potential therapeutic for nephropathic cystinosis. |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 - H315 - H319 - H335 |
Precautionary statements | P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xn |
Risk Statements | 22-36/37/38 |
Safety Statements | 26-36 |
RIDADR | UN 3335 |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98.0% (RT) |
Storage Temp. | 2-8°C |
UNSPSC | 12352116 |