L-Cysteine
SIGMA/30089 - BioUltra, ≥98.5% (RT)
Synonym: (R)
CAS Number: 52-90-4
Empirical Formula (Hill Notation): C3H7NO2S
Molecular Weight: 121.16
EC Number: 200-158-2
MDL Number: MFCD00064306
Linear Formula: HSCH2CH(NH2)CO2H
Product Type: Chemical
| λ | 1 M in 1 M HCl |
| anion traces | chloride (Cl-): ≤100 mg/kg |
| sulfate (SO42-): ≤50 mg/kg | |
| assay | ≥98.5% (RT) |
| cation traces | Al: ≤5 mg/kg |
| As: ≤0.1 mg/kg | |
| Ba: ≤5 mg/kg | |
| Bi: ≤5 mg/kg | |
| Ca: ≤10 mg/kg | |
| Cd: ≤5 mg/kg | |
| Co: ≤5 mg/kg | |
| Cr: ≤5 mg/kg | |
| Cu: ≤5 mg/kg | |
| Fe: ≤5 mg/kg | |
| K: ≤50 mg/kg | |
| Li: ≤5 mg/kg | |
| Mg: ≤5 mg/kg | |
| Mn: ≤5 mg/kg | |
| Mo: ≤5 mg/kg | |
| Na: ≤100 mg/kg | |
| NH4+: ≤500 mg/kg | |
| Ni: ≤5 mg/kg | |
| Pb: ≤5 mg/kg | |
| Sr: ≤5 mg/kg | |
| Zn: ≤5 mg/kg | |
| color | white |
| form | powder or crystals |
| ign. residue | ≤0.05% (as SO4) |
| impurities | insoluble matter, passes filter test |
| ≤0.5% foreign amino acids | |
| InChI | 1S/C3H7NO2S/c4-2(1-7)3(5) |
| InChI key | XUJNEKJLAYXESH-REOHCLBHSA |
| loss | ≤0.05% loss on drying, 20 °C (HV) |
| mp | 240 °C (dec.) (lit.) |
| optical activity | [α]20/D +8.0±0.5°, c = 5% in 5 M HCl |
| product line | BioUltra |
| Quality Level | 200  |
| SMILES string | N[C@@H](CS)C(O)=O |
| solubility | 1 M HCl: 1 M at 20 °C, clear, colorless |
| technique(s) | HPLC: suitable |
| UV absorption | λ: 260 nm Amax: 1.5 |
| λ: 280 nm Amax: 0.2 |
| Application: | L-Cysteine has been used in quenching of unreacted maleimide during antibody grafting. It has also been used in the preparation of nitrosocysteine stock solution, that has been employed to induce S-nitrosylation to achieve reversible cysteine modification. |
| Biochem/physiol Actions: | Cysteine is one of the functional amino acids that regulates metabolism for growth, reproduction, maintenance and immunity. Cysteine provides the disulfide linkage in proteins. It is directly associated with the transport of sulfur. Taurine, a metabolic product of cysteine acts as an antioxidant and controls the cellular redox state. Cysteine is involved in the formation of hydrogen sulfide that is utilized as a signaling molecule. |
| Biochem/physiol Actions: | NMDA glutamatergic receptor agonist. |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Purity | ≥98.5% (RT) |
| mp | 240 °C (dec.) (lit.) |
| UNSPSC | 12352209 |