L-Cystine
SIGMA/30200 - ≥99.7% (TLC)
Synonym: (R,R)-3,3′-Dithiobis(2-aminopropionicacid)
CAS Number: 56-89-3
Empirical Formula (Hill Notation): C6H12N2O4S2
Molecular Weight: 240.30
EC Number: 200-296-3
MDL Number: MFCD00064228
Linear Formula: [-SCH2CH(NH2)CO2H]2
Product Type: Chemical
anion traces | chloride (Cl-): ≤500 mg/kg |
sulfate (SO42-): ≤100 mg/kg | |
application(s) | peptide synthesis |
assay | ≥99.7% (TLC) |
cation traces | Ca: ≤50 mg/kg |
Cd: ≤5 mg/kg | |
Co: ≤5 mg/kg | |
Cr: ≤5 mg/kg | |
Cu: ≤6 mg/kg | |
Fe: ≤10 mg/kg | |
K: ≤50 mg/kg | |
Mg: ≤5 mg/kg | |
Mn: ≤5 mg/kg | |
Na: ≤150 mg/kg | |
Ni: ≤5 mg/kg | |
Pb: ≤5 mg/kg | |
Zn: ≤5 mg/kg | |
color | white |
form | powder or crystals |
ign. residue | ≤0.1% (as SO4) |
InChI | 1S/C6H12N2O4S2/c7-3(5(9)1 |
InChI key | LEVWYRKDKASIDU-IMJSIDKUSA |
loss | ≤0.1% loss on drying |
mp | >240 °C (dec.) (lit.) |
optical activity | [α]20/D −219±5°, c = 1% in 1 M HCl |
Quality Level | 200 |
SMILES string | N[C@@H](CSSC[C@H](N)C(O)= |
solubility | 1 M HCl: 0.5 g/10 mL, clear, colorless |
Application: | L-Cystine has been used to prepare stock solution which in turn is utilized for determining the L-cysteine and L-cystine in pharmaceutical preparations as well as in urine samples by using spectrofluorimetric flow injection method. |
Biochem/physiol Actions: | Cystine is required for the synthesis of glutathione that protects the cells from oxidative stress. A specific x(c)-cysteine/glutamate antiporter mediates cellular uptake of cysteine in exchange for glutamate. Inhibition of cysteine uptake induces toxicity in neuronal cells. |
Other Notes: | Preparation of N,N′-dibenzoyl-L-cystine, an efficient auxiliary for enantioselective reductions of ketones |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99.7% (TLC) |
mp | >240 °C (dec.) (lit.) |
UNSPSC | 12352209 |