Cytidine 5′-diphosphocholine sodium salt hydrate

SIGMA/30290 - ≥99.0% (HPLC)

Synonym: CDP-choline-Na

CAS Number: 33818-15-4 (anhydrous)
Empirical Formula (Hill Notation): C₁₄H₂₅N₄NaO₁₁P₂ · xH₂O
Molecular Weight: 510.31 (anhydrous basis)
MDL Number: MFCD00150508
Linear Formula: C₁₄H₂₅N₄NaO₁₁P₂ · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-30290-250MG	250 mg	$258.00 1/EAAdd To Favorites	Add To Favorites
45-30290-1G	1 g	$566.00 1/EAAdd To Favorites	Add To Favorites

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assay	≥99.0% (HPLC)
biological source	synthetic
form	powder
impurities	≤8% water
InChI	1S/C14H26N4O11P2.Na/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21;/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25);/q;+1/p-1/t9?,11-,12-,13?;/m1./s1
InChI key	YWAFNFGRBBBSPD-MBWJOHGMSA-M
Quality Level	100
SMILES string	[Na+].C[N+](C)(C)CCOP([O-])(=O)OP([O-])(=O)OCC1OC([C@H](O)[C@@H]1O)N2C=CC(N)=NC2=O
storage temp.	2-8°C

Application:	Cytidine 5′-diphosphocholine (CDP-choline) is generated by choline-phosphate cytidylyltransferase EC 2.7.7.15 in support of the synthesis of phosphatidylcholine. CDP-choline is being used in studies of its affects on neurorecovery.
Application:	Cytidine 5′-diphosphocholine sodium salt hydrate has been used as a component of the mixture during the ribonucleotide reductase (RNR) assay in mouse primary pancreatic acinar cells.
Biochem/physiol Actions:	Cytidine 5′-diphosphocholine (CDP-choline) is an endogenous compound that plays an important role in the synthesis of phospholipids in the cell membrane. It acts as a choline donor for the biosynthesis of acetylcholine and phosphatidylcholine, a neuronal membrane phospholipid. CDP-choline enhances brain metabolism and influences the levels of various neurotransmitters including dopamine, epinephrine, and acetylcholine. It has been studied as a neuroprotectant after cerebral ischemia. CDP-choline is observed to exhibit therapeutic effects against cognitive impairment arising from multiple causes, cerebral vascular diseases, after-head trauma, and Alzheimer′s disease.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99.0% (HPLC)
Storage Temp.	2-8°C
UNSPSC	41106305