Cytidine 5′-diphosphocholine sodium salt hydrate
SIGMA/30290 - ≥99.0% (HPLC)
Synonym: CDP-choline-Na
CAS Number: 33818-15-4 (anhydrous)
Empirical Formula (Hill Notation): C14H25N4NaO11P2 · xH2O
Molecular Weight: 510.31 (anhydrous basis)
MDL Number: MFCD00150508
Linear Formula: C14H25N4NaO11P2 · xH2O
Product Type: Chemical
assay | ≥99.0% (HPLC) |
biological source | synthetic |
form | powder |
impurities | ≤8% water |
InChI | 1S/C14H26N4O11P2.Na/c1-18 |
InChI key | YWAFNFGRBBBSPD-MBWJOHGMSA |
Quality Level | 100 |
SMILES string | [Na+].C[N+](C)(C)CCOP([O- |
storage temp. | 2-8°C |
Application: | Cytidine 5′-diphosphocholine (CDP-choline) is generated by choline-phosphate cytidylyltransferase EC 2.7.7.15 in support of the synthesis of phosphatidylcholine. CDP-choline is being used in studies of its affects on neurorecovery. |
Application: | Cytidine 5′-diphosphocholine sodium salt hydrate has been used as a component of the mixture during the ribonucleotide reductase (RNR) assay in mouse primary pancreatic acinar cells. |
Biochem/physiol Actions: | Cytidine 5′-diphosphocholine (CDP-choline) is an endogenous compound that plays an important role in the synthesis of phospholipids in the cell membrane. It acts as a choline donor for the biosynthesis of acetylcholine and phosphatidylcholine, a neuronal membrane phospholipid. CDP-choline enhances brain metabolism and influences the levels of various neurotransmitters including dopamine, epinephrine, and acetylcholine. It has been studied as a neuroprotectant after cerebral ischemia. CDP-choline is observed to exhibit therapeutic effects against cognitive impairment arising from multiple causes, cerebral vascular diseases, after-head trauma, and Alzheimer′s disease. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99.0% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 41106305 |