Sodium deoxycholate

SIGMA/30970 - BioXtra, ≥98.0% (dry matter, NT)

Synonym: 3α,12α-Dihydroxy-5β-cholanic acid sodium salt; 7-Deoxycholic acid sodium salt; Desoxycholic acid sodium salt

CAS Number: 302-95-4
Empirical Formula (Hill Notation): C₂₄H₃₉NaO₄
Molecular Weight: 414.55
EC Number: 206-132-7
MDL Number: MFCD00064139
Linear Formula: C₂₄H₃₉NaO₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-30970-25G	25 g	$61.70 1/EAAdd To Favorites	Add To Favorites
45-30970-100G	100 g	$168.00 1/EAAdd To Favorites	Add To Favorites
45-30970-500G	500 g	$667.00 1/EAAdd To Favorites	Add To Favorites

aggregation number	3-12
assay	≥98.0% (dry matter, NT)
biological source	ox bile
cation traces	Ca: ≤500 mg/kg
	Cd: ≤5 mg/kg
	Co: ≤5 mg/kg
	Cr: ≤5 mg/kg
	Cu: ≤5 mg/kg
	Fe: ≤10 mg/kg
	Mg: ≤10 mg/kg
	Mn: ≤5 mg/kg
	Ni: ≤5 mg/kg
	Pb: ≤10 mg/kg
	Zn: ≤5 mg/kg
CMC	2-6 mM (20-25°C)
description	anionic
form	powder
functional group	carboxylic acid
HLB	16
impurities	≤1% cholic acid (HPLC)
	≤6% water
InChI	1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
InChI key	FHHPUSMSKHSNKW-SMOYURAASA-M
mol wt	micellar avg mol wt 1200-5000
optical activity	[α]20/D +44±2°, c = 2% in H₂O
product line	BioXtra
Quality Level	300
SMILES string	[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
solubility	water: soluble 1 gm in 10 ml, clear, colorless to very faintly yellow
technique(s)	DNA purification: suitable
	electrophoresis: suitable
	RNA purification: suitable

Application:	Sodium deoxycholate has been used for preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins.
Biochem/physiol Actions:	Sodium deoxycholate is a bile salt that stimulates the apical to basolateral accumulation of epirubicin in Caco-2 cells as well as increased serosal absorption of epirubicin in the rat jejunum and ileum. Sodium deoxycholate dissociates histones II from DNA as well as causes lysis of the viral membrane.
Features and Benefits:	• Suitable for Cell Biology and Biochemical Research • Can be used in Electrophoresis, DNA and RNA purification • Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications. • High purity product for research applications
General description:	Sodium Deoxycholate, a bile acid derivative, is a crucial component in biochemical and cell biology research. This water-soluble detergent is widely used in protein-related experiments, including cell lysates and liposome preparation. It aids in membrane protein extraction, lipid compound extraction, and cell nucleus separation. Sodium Deoxycholate is also applied in cholesterol flocculation tests and affinity chromatography for column elution or regeneration. It is commonly used in microbiology for cell lysing, especially because it can be removed from the solution via dialysis. Sodium Deoxycholate is also utilized in eluting buffers for affinity chromatography and plays a crucial role in DNA and RNA extraction from cells and tissues in molecular biology applications. Additionally, it is used as a catalyst in the preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins.
Other Notes:	2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
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Packaging:	25, 100, 500 g in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 - H412
Precautionary statements	P264 - P270 - P273 - P301 + P312 - P501
Hazard Codes	Xn
Risk Statements	22-37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98.0% (dry matter, NT)
UNSPSC	12161900