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Dextran sulfate sodium salt from Leuconostoc spp.

SIGMA/31404 - Mr 5,000

CAS Number: 9011-18-1
MDL Number: MFCD00081551
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-31404-5G-F 5 g
$61.10
1/EA
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45-31404-25G-F 25 g
$292.00
1/EA
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biological source (Leuconostoc spp.)
composition Sulfur Content, 16.0-20.0%
form powder
loss ≤10% loss on drying
mol wt Mr 5,000
Quality Level 200 
solubility H2O: 0.1 g/mL, clear, colorless to slightly yellow
  H2O: freely soluble 50 mg/mL, clear
  water: 100 g/L at 25 °C (77 °F )
storage temp. room temp
useful pH range 6.0-8.0 (10 g/L)
Application: Dextran sulfate sodium salt from Leuconostoc sp. is a polyanion used as a test reagent for testing its capability to rupture the extracellular enveloped virus (EEV) outer membrane. It has also been used for assessing the impact of TLR4 monoclonal antibody on the growth of dextran-sulfate-sodium-(DSS)-induced colitis.
Biochem/physiol Actions: Dextran is a mixture of glucose polymers of varying size and geometry.Dextran in the form of dextran sulphate sodium acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength. The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.
Other Notes: To gain a comprehensive understanding of our extensive range of Dextrans  for your research, we encourage you to visit our Carbohydrates  Category page.
Preparation Note: prepared from dextran with Mr ~5000
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. room temp
UNSPSC 12161700

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