Barbital
SIGMA/31995 - BioXtra, ≥99.0% (T)
Synonym: 5,5-
CAS Number: 57-44-3
Empirical Formula (Hill Notation): C8H12N2O3
Molecular Weight: 184.19
EC Number: 200-331-2
MDL Number: MFCD00036212
Linear Formula: C8H12N2O3
Product Type: Chemical
anion traces | chloride (Cl-): ≤500 mg/kg |
sulfate (SO42-): ≤50 mg/kg | |
application(s) | forensics and toxicology pharmaceutical (small molecule) veterinary |
assay | ≥99.0% (T) |
cation traces | Ca: ≤50 mg/kg |
Cd: ≤5 mg/kg | |
Co: ≤5 mg/kg | |
Cr: ≤5 mg/kg | |
Cu: ≤5 mg/kg | |
Fe: ≤5 mg/kg | |
K: ≤50 mg/kg | |
Mg: ≤5 mg/kg | |
Mn: ≤5 mg/kg | |
Na: ≤200 mg/kg | |
Ni: ≤5 mg/kg | |
Pb: ≤5 mg/kg | |
Zn: ≤5 mg/kg | |
drug control | USDEA Schedule IV; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal) |
ign. residue | ≤0.1% (as SO4) |
InChI | 1S/C8H12N2O3/c1-3-8(4-2)5 |
InChI key | FTOAOBMCPZCFFF-UHFFFAOYSA |
loss | ≤0.5% loss on drying, 20 °C (HV) |
mp | 189-191 °C |
product line | BioXtra |
Quality Level | 200 |
SMILES string | CCC1(CC)C(=O)NC(=O)NC1=O |
solubility | acetone: soluble |
alcohol: soluble 1 gm in 14 ml | |
chloroform: soluble 1 gm in 75 ml | |
diethyl ether: soluble 1 gm in 35 ml | |
ethyl acetate: soluble | |
nitrobenzene: soluble | |
petroleum ether: soluble | |
pyridine: soluble | |
water: soluble 1 gm in 13 ml (boiling) | |
water: soluble 1 gm in 130 ml | |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Application: | Barbital has been used as an assay buffer for determining the carbonic anhydrase activity. It has also been used for rocket immunoelectrophoresis. |
Biochem/physiol Actions: | Barbital also referred to as 5,5-Diethylbarbituric acid, Barbitone or Veronal is a sedative/hypnotic (sleeping aid). It stimulates the development of tumors in rats treated with a sub-effective dose of N-bis(2-hydroxypropyl)nit |
Biochem/physiol Actions: | Sedative/hypnotic |
Other Notes: | Sales restrictions may apply |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99.0% (T) |
mp | 189-191 °C |
UNSPSC | 12352111 |