PLAP (SP15) Rabbit Monoclonal Antibody
SIGMA/321R-1
Product Type: Chemical
Immunohistochemistry PLAP (SP15) on seminoma tissue
| antibody form | culture supernatant |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | SP15, monoclonal |
| conjugate | unconjugated |
| control | placenta |
| description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| form | buffered aqueous solution |
| isotype | IgG |
| manufacturer/tradename | Cell Marque® |
| packaging | bottle of 1.0 mL predilute (321R-17) |
| bottle of 7.0 mL predilute (321R-18) | |
| vial of 0.1 mL concentrate (321R-14) | |
| vial of 0.5 mL concentrate (321R-15) | |
| vial of 1.0 mL concentrate (321R-16) | |
| Quality Level | 100  |
| 500 |
|
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:1000 |
| visualization | cytoplasmic |
| Analysis Note: |
|
||||
| General description: | Anti-PLAP immunoreacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease. This antibody has shown cross-reaction with human intestinal alkaline phosphatase. | ||||
| Legal Information: | Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany | ||||
| Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
| Other Notes: | PLAP Positive Control Slides, Product No. 321S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). |
||||
| Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide | ||||
| Preparation Note: | Download the IFU specific to your product lot and format  Note: This requires a keycode which can be found on your packaging or product label. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |