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Neomycin trisulfate salt hydrate

SIGMA/33492 - VETRANAL®, analytical standard

CAS Number: 1405-10-3
Empirical Formula (Hill Notation): C23H46N6O13 · 3H2SO4 · xH2O
Molecular Weight: 908.88 (anhydrous basis)
EC Number: 215-773-1
Linear Formula: C23H46N6O13 · 3H2SO4 · xH2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-33492-100MG-R 100 mg
 $48.10
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application(s) clinical testing
format neat
grade analytical standard
InChI 1S/C23H46N6O13.3H2O4S.H2O/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;3*1-5(2,3)4;/h5-23,30-36H,1-4,24-29H2;3*(H2,1,2,3,4);1H2/t5-,6+,7-,8+,9-,10-,11?,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;;;;/m1..../s1
InChI key WHAGUNPVKDUVFV-QGTTWHFQSA-N
product line VETRANAL®
Quality Level 100 
shelf life limited shelf life, expiry date on the label
SMILES string O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@@H](O[C@@H]2CO)O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N)C(N)[C@@H](O)[C@@H]1O
storage temp. 2-8°C
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
Biochem/physiol Actions: Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons.

Antimicrobial spectrum: Neomycin acts against both gram-positive and gram-negative bacteria.
General description: Chemical structure: aminoglycoside
Legal Information: VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Temp. 2-8°C
UNSPSC 41116107

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