TTF-1 (EP229) Rabbit Monoclonal Primary Antibody
SIGMA/343R-1
Product Type: Chemical
antibody form | culture supernatant |
antibody product type | primary antibodies |
biological source | rabbit |
clone | EP229, monoclonal |
conjugate | unconjugated |
control | lung adenocarcinoma |
description | (For In Vitro Diagnostic Use in Select Regions (See Chart)) |
form | buffered aqueous solution |
isotype | IgG |
manufacturer/tradename | Cell Marque™ |
packaging | bottle of 1.0 mL predilute (343R-17) |
bottle of 7.0 mL predilute (343R-18) | |
vial of 0.1 mL concentrate (343R-14) | |
vial of 0.5 mL concentrate (343R-15) | |
vial of 1.0 mL concentrate (343R-16) | |
Quality Level | 100 |
500 | |
shipped in | wet ice |
species reactivity | human |
storage temp. | 2-8°C |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 |
visualization | nuclear |
General description: | Anti-TTF-1 (Thyroid Transcription Factor 1) is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the organs rather than thyroid1-2, germ cell tumors3, and malignant mesothelioma.4-5 It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.6 TTF-1 labeling is also seen in thyroid and thyroid-derived tumors.7 TTF-1 immunostaining is useful in the differentiation between pulmonary and nonpulmonary origin of adenocarcinomas in malignant effusions.8 TTF-1 staining is very reliable in discerning whether a brain metastasis has arisen from a pulmonary or nonpulmonary site, particularly when dealing with adenocarcinomas and large-cell carcinomas.9 | ||||
Legal Information: | Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany | ||||
Linkage: | TTF-1 Positive Control Slides, Product No. 343S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). | ||||
Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide. | ||||
Preparation Note: | Download the IFU specific to your product lot and format Note: This requires a keycode which can be found on your packaging or product label. | ||||
Quality: |
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RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |