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Artemisinin

SIGMA/361593 - 98%

Synonym: Arteannuin; Qinghaosu

CAS Number: 63968-64-9
Empirical Formula (Hill Notation): C15H22O5
Molecular Weight: 282.33
MDL Number: MFCD00081057
Linear Formula: C15H22O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-361593-100MG 100 mg
 $104.00
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antibiotic activity spectrum parasites
  viruses
application(s) metabolomics
vitamins, nutraceuticals, and natural products
assay 98%
form solid
InChI 1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1
InChI key BLUAFEHZUWYNDE-NNWCWBAJSA-N
mode of action enzyme | inhibits
mp 156-157 °C (lit.)
optical activity [α]20/D +76°, c = 0.5 in methanol
Quality Level 100 
SMILES string C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4
Application: Artemisinin has been used:
• in drug susceptibility assays
• as a standard for its quantification from artemisinin from hairy roots
• to check cell viability using 3-(4, 5-dimethylthiazol-2yl)-2,5-diphenyl tetrazolium bromide (MTT) assay
• as an antimalarial agent to investigate the role of autophagy-related (ATG) genes throughout the P. falciparum asexual and sexual blood stages
Biochem/physiol Actions: Artemisinin (Qinghaosu), a sesquiterpene lactone, is a highly active anti-malarial (falciparum malaria) drug. Artemisinin is also an anthelmintic (parasitic worm) effective against the blood fluke, schistosomiasis.
General description: Artemisinin is extracted from sweet wormwood (Artemisia annua). It has anticancer, antiprotozoal and antiviral activities. Artemisinin is associated with brainstem encephalopathy.
Packaging: 100 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity 98%
mp 156-157 °C (lit.)
UNSPSC 12352205

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