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Hydroxystilbamidine bis(methanesulfonate)

SIGMA/39286 - suitable for fluorescence, ≥96.0% (HPLC)

Synonym: 2-Hydroxystilbene-4,4′-dicarboxamidine bis(methanesulfonate); Fluoro-Gold; 2-Hydroxystilbene-4,4′-dicarboxamidine bis(methanesulfonate)

CAS Number: 223769-64-0
Empirical Formula (Hill Notation): C18H24N4O7S2
Molecular Weight: 472.54
MDL Number: MFCD01863083
Linear Formula: C18H24N4O7S2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-39286-10MG-F 10 mg
 $1060.00
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assay ≥96.0% (HPLC)
fluorescence λex 318 nm; λem 560 nm in TBE Buffer
form powder
InChI 1S/C16H16N4O.2CH4O3S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*1-5(2,3)4/h1-9,21H,(H3,17,18)(H3,19,20);2*1H3,(H,2,3,4)/b4-1+;;
InChI key YGNSQKCULHSJDC-HFPMQDOPSA-N
Quality Level 100 
SMILES string CS(O)(=O)=O.CS(O)(=O)=O.NC(=N)c1ccc(cc1)C=Cc2ccc(cc2O)C(N)=N
storage temp. 2-8°C
suitability suitable for fluorescence
Application: Hydroxystilbamidine bis(methanesulfonate), a fluorescent retrograde tracer (axonal transport), is used for neural mapping in microanatomical research.
Application: Hydroxystilbamidine bis (methanesulfonate) or Fluoro-Gold (FG) is used to label neurons and investigate the early effects of hearing loss. It is used to study morphological features of extensive axonal projections within the CNS by labelling the cells.
General description: Hydroxystilbamidine bis (methanesulfonate), also known as Fluoro-Gold, is a retrograde fluorescent tracer. Chemically, Hydroxystilbamidine is a weak base and can cross cell membranes in its uncharged form.

A few properties of Hydroxystilbamidine bis (methanesulfonate) are:

•  Intense Fluorescence.
•  Extensive filling of dendrites.
•  High Resistance to fading.
•  No uptake by undamaged fibers.
•  No diffusion from labelled cells.
•  Highly compatible with other neuro-histochemical techniques.
Purity ≥96.0% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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