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Pyrimidine nucleoside phosphorylase

SIGMA/39488 - recombinant, expressed in E. coli, ≥1300 U/mL

CAS Number: 9055-35-0
MDL Number: MFCD00011685
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-39488-1ML 1 mL
$228.00
1/EA
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45-39488-5ML 5 mL
$891.00
1/EA
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

form liquid
Quality Level 100 
recombinant expressed in E. coli
relevant disease(s) cancer
specific activity ≥1300 U/mL
storage temp. −20°C
Application: Pyrimidine nucleoside phosphorylase (PyNPase) may be used as a marker to predict the malignant potential of breast cancer, especially lymph node metastasis. PyNPase is used to study breast cancer, specifically its role in angiogenesis.
Biochem/physiol Actions: Pyrimidine nucleoside phosphorylase (PyNPase) is a glycosyltransferase that catalyzes the conversion of pyrimidine nucleoside and phosphate to a pyrimidine base and α-D-ribose 1-phosphate. PyNPase plays a significant role in breast cancer angiogenesis.
Other Notes: One unit will convert 1 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per minute at pH 7.4 and 25°C
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
activity specific activity: ≥1300 U/mL
Storage Temp. −20°C
Enzyme Commission (EC) Number 2.4.2.2   ( BRENDA  | IUBMB  )
UNSPSC 12352204

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