C4d Rabbit Polyclonal Antibody
SIGMA/404A-1
Product Type: Chemical
antibody form | Ig fraction of antiserum |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
conjugate | unconjugated |
control | lymph node, tonsil |
description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
form | buffered aqueous solution |
manufacturer/tradename | Cell Marque™ |
packaging | bottle of 1.0 mL predilute (404A-17) |
bottle of 7.0 mL predilute (404A-18) | |
vial of 0.1 mL concentrate (404A-14) | |
vial of 0.5 mL concentrate (404A-15) | |
vial of 1.0 mL concentrate (404A-16) | |
Quality Level | 100 |
500 | |
shipped in | wet ice |
species reactivity | human |
storage temp. | 2-8°C |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 |
visualization | cytoplasmic, membranous |
General description: | C4d is a stable split product remnant of classical complement activation which becomes covalently bound to endothelium and basement membrane, after induction of the classical antibody-induced pathway. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in both chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival and is an aid in treating acute rejection. | ||||
Legal Information: | Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany | ||||
Linkage: | C4d Positive Control Slides, Product No. 404S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). | ||||
Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide | ||||
Preparation Note: | Download the IFU specific to your product lot and format Note: This requires a keycode which can be found on your packaging or product label. | ||||
Quality: |
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RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |