Synonym: (2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt; L-Carnitine propionyl ester; C3-Carnitine; Propanoyl-L-carnitine
CAS Number: 20064-19-1
Empirical Formula (Hill Notation): C10H19NO4
Molecular Weight: 217.26
MDL Number: MFCD00870024
Linear Formula: C10H19NO4
Product Type: Chemical
assay |
≥94.0% (HPLC) |
color |
white to off-white |
form |
powder or crystals |
impurities |
≤10% water (calcd. from elemental analysis) |
InChI |
1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1 |
InChI key |
UFAHZIUFPNSHSL-MRVPVSSYSA-N |
optical activity |
[α]/D -23±3°, c = 1 in H2O |
Quality Level |
100 |
SMILES string |
[O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O |
storage temp. |
2-8°C |
technique(s) |
LC/MS: suitable |
Application: |
Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS). |
Biochem/physiol Actions: |
Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA. |
General description: |
Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine. |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥94.0% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
12352209 |